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In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis.
Silva DKC, Teixeira JS, Moreira DRM, da Silva TF, Barreiro EJL, de Freitas HF, Pita SSDR, Teles ALB, Guimarães ET, Soares MBP. Silva DKC, et al. Among authors: moreira drm. Front Pharmacol. 2020 Dec 16;11:590544. doi: 10.3389/fphar.2020.590544. eCollection 2020. Front Pharmacol. 2020. PMID: 33390966 Free PMC article.
Potent immunosuppressive activity of a phosphodiesterase-4 inhibitor N-acylhydrazone in models of lipopolysaccharide-induced shock and delayed-type hypersensitivity reaction.
Guimarães ET, Dos Santos TB, Silva DKC, Meira CS, Moreira DRM, da Silva TF, Salmon D, Barreiro EJ, Soares MBP. Guimarães ET, et al. Among authors: moreira drm. Int Immunopharmacol. 2018 Dec;65:108-118. doi: 10.1016/j.intimp.2018.09.047. Epub 2018 Oct 9. Int Immunopharmacol. 2018. PMID: 30312879
Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization.
Meira CS, Santos ES, Santo RFDE, Vasconcelos JF, Orge ID, Nonaka CKV, Barreto BC, Caria ACI, Silva DN, Barbosa-Filho JM, Macambira SG, Moreira DRM, Soares MBP. Meira CS, et al. Among authors: moreira drm. Front Immunol. 2019 Jun 11;10:1257. doi: 10.3389/fimmu.2019.01257. eCollection 2019. Front Immunol. 2019. PMID: 31244833 Free PMC article.
Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
Moraes ADTO, Miranda MDS, Jacob ÍTT, Amorim CADC, Moura RO, Silva SÂSD, Soares MBP, Almeida SMV, Souza TRCL, Oliveira JF, Silva TGD, Melo CML, Moreira DRM, Lima MDCA. Moraes ADTO, et al. Among authors: moreira drm. Bioorg Med Chem. 2018 Nov 1;26(20):5388-5396. doi: 10.1016/j.bmc.2018.07.024. Epub 2018 Jul 17. Bioorg Med Chem. 2018. PMID: 30293795
69 results