Pedersen SW - Search Results

1

Targeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation.

Bartling CRO, Jensen TMT, Henry SM, Colliander AL, Sereikaite V, Wenzler M, Jain P, Maric HM, Harpsøe K, Pedersen SW, Clemmensen LS, Haugaard-Kedström LM, Gloriam DE, Ho A, Strømgaard K. Bartling CRO, et al. Among authors: pedersen sw. J Am Chem Soc. 2021 Jan 20;143(2):891-901. doi: 10.1021/jacs.0c10696. Epub 2021 Jan 5. J Am Chem Soc. 2021. PMID: 33398998 Free PMC article.

2

Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction.

Bach A, Chi CN, Olsen TB, Pedersen SW, Røder MU, Pang GF, Clausen RP, Jemth P, Strømgaard K. Bach A, et al. Among authors: pedersen sw. J Med Chem. 2008 Oct 23;51(20):6450-9. doi: 10.1021/jm800836w. Epub 2008 Sep 24. J Med Chem. 2008. PMID: 18811137

3

Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction.

Bach A, Eildal JN, Stuhr-Hansen N, Deeskamp R, Gottschalk M, Pedersen SW, Kristensen AS, Strømgaard K. Bach A, et al. Among authors: pedersen sw. J Med Chem. 2011 Mar 10;54(5):1333-46. doi: 10.1021/jm1013924. Epub 2011 Feb 15. J Med Chem. 2011. PMID: 21322614

4

Synthesis of peptides using tert-butyloxycarbonyl (Boc) as the α-amino protection group.

Pedersen SW, Armishaw CJ, Strømgaard K. Pedersen SW, et al. Methods Mol Biol. 2013;1047:65-80. doi: 10.1007/978-1-62703-544-6_4. Methods Mol Biol. 2013. PMID: 23943478

5

Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations.

Pedersen SW, Pedersen SB, Anker L, Hultqvist G, Kristensen AS, Jemth P, Strømgaard K. Pedersen SW, et al. Among authors: pedersen sb. Nat Commun. 2014;5:3215. doi: 10.1038/ncomms4215. Nat Commun. 2014. PMID: 24477114 Free article.

6

The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain.

Pedersen SW, Hultqvist G, Strømgaard K, Jemth P. Pedersen SW, et al. PLoS One. 2014 Apr 18;9(4):e95619. doi: 10.1371/journal.pone.0095619. eCollection 2014. PLoS One. 2014. PMID: 24748272 Free PMC article.

7

Ligand binding to the PDZ domains of postsynaptic density protein 95.

Toto A, Pedersen SW, Karlsson OA, Moran GE, Andersson E, Chi CN, Strømgaard K, Gianni S, Jemth P. Toto A, et al. Among authors: pedersen sw. Protein Eng Des Sel. 2016 May;29(5):169-75. doi: 10.1093/protein/gzw004. Epub 2016 Mar 2. Protein Eng Des Sel. 2016. PMID: 26941280

8

Importance of a Conserved Lys/Arg Residue for Ligand/PDZ Domain Interactions as Examined by Protein Semisynthesis.

Pedersen SW, Moran GE, Sereikaitė V, Haugaard-Kedström LM, Strømgaard K. Pedersen SW, et al. Chembiochem. 2016 Oct 17;17(20):1936-1944. doi: 10.1002/cbic.201600322. Epub 2016 Sep 7. Chembiochem. 2016. PMID: 27472651

9

Site-Specific Phosphorylation of PSD-95 PDZ Domains Reveals Fine-Tuned Regulation of Protein-Protein Interactions.

Pedersen SW, Albertsen L, Moran GE, Levesque B, Pedersen SB, Bartels L, Wapenaar H, Ye F, Zhang M, Bowen ME, Strømgaard K. Pedersen SW, et al. ACS Chem Biol. 2017 Sep 15;12(9):2313-2323. doi: 10.1021/acschembio.7b00361. Epub 2017 Aug 1. ACS Chem Biol. 2017. PMID: 28692247 Free PMC article.

10

Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction.

Balboa JR, Essig DJ, Ma S, Karer N, Clemmensen LS, Pedersen SW, Joerger AC, Knapp S, Østergaard S, Strømgaard K. Balboa JR, et al. Among authors: pedersen sw. J Med Chem. 2023 Jan 12;66(1):976-990. doi: 10.1021/acs.jmedchem.2c01803. Epub 2022 Dec 29. J Med Chem. 2023. PMID: 36580549

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