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Evaluating Patients With Impaired Renal Function During Drug Development: Highlights From the 2019 US FDA Pharmaceutical Science and Clinical Pharmacology Advisory Committee Meeting.
Sahre MD, Milligan L, Madabushi R, Graham RA, Reynolds KS, Terzic A, Benjamin J, Burckart GJ, Huang SM, Schuck R, Thompson AM, Zineh I. Sahre MD, et al. Among authors: schuck r. Clin Pharmacol Ther. 2021 Aug;110(2):285-288. doi: 10.1002/cpt.2151. Epub 2021 Feb 16. Clin Pharmacol Ther. 2021. PMID: 33411946
Effectiveness of clopidogrel dose escalation to normalize active metabolite exposure and antiplatelet effects in CYP2C19 poor metabolizers.
Horenstein RB, Madabushi R, Zineh I, Yerges-Armstrong LM, Peer CJ, Schuck RN, Figg WD, Shuldiner AR, Pacanowski MA. Horenstein RB, et al. Among authors: schuck rn. J Clin Pharmacol. 2014 Aug;54(8):865-73. doi: 10.1002/jcph.293. Epub 2014 Apr 7. J Clin Pharmacol. 2014. PMID: 24710841 Free PMC article. Clinical Trial.
Considerations for Developing Targeted Therapies in Low-Frequency Molecular Subsets of a Disease.
Schuck RN, Woodcock J, Zineh I, Stein P, Jarow J, Temple R, Permutt T, LaVange L, Beaver JA, Charlab R, Blumenthal GM, Dorff SE, Leptak C, Lemery S, Rogers H, Chowdhury B, Litwack ED, Pacanowski M. Schuck RN, et al. Clin Pharmacol Ther. 2018 Aug;104(2):282-289. doi: 10.1002/cpt.1041. Epub 2018 Feb 23. Clin Pharmacol Ther. 2018. PMID: 29473145 Free PMC article. Review.
96 results