Dingemanse J - Search Results

1

Insights from In Vitro and Clinical Data to Guide Transition from the Novel P2Y12 Antagonist Selatogrel to Clopidogrel, Prasugrel, and Ticagrelor.

Schilling U, Dingemanse J, Dobrow M, Baumann M, Riederer MA, Juif PE, Ufer M. Schilling U, et al. Among authors: dingemanse j. Thromb Haemost. 2021 Jun;121(6):755-766. doi: 10.1055/s-0040-1721773. Epub 2021 Jan 7. Thromb Haemost. 2021. PMID: 33412611 Clinical Trial.

2

Pharmacokinetics of the novel dual endothelin receptor antagonist macitentan in subjects with hepatic or renal impairment.

Sidharta PN, Lindegger N, Ulč I, Dingemanse J. Sidharta PN, et al. Among authors: dingemanse j. J Clin Pharmacol. 2014 Mar;54(3):291-300. doi: 10.1002/jcph.193. J Clin Pharmacol. 2014. PMID: 24122797 Clinical Trial.

3

Multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ponesimod, an S1P1 receptor modulator: favorable impact of dose up-titration.

Brossard P, Scherz M, Halabi A, Maatouk H, Krause A, Dingemanse J. Brossard P, et al. Among authors: dingemanse j. J Clin Pharmacol. 2014 Feb;54(2):179-88. doi: 10.1002/jcph.244. Epub 2014 Jan 9. J Clin Pharmacol. 2014. PMID: 24408162 Clinical Trial.

4

Single- and multiple-dose tolerability and pharmacokinetics of the CRTH2 antagonist setipiprant in healthy male subjects.

Sidharta PN, Diamant Z, Dingemanse J. Sidharta PN, et al. Among authors: dingemanse j. Fundam Clin Pharmacol. 2014 Dec;28(6):690-9. doi: 10.1111/fcp.12079. Epub 2014 May 11. Fundam Clin Pharmacol. 2014. PMID: 24734908 Clinical Trial.

5

Investigation of mutual pharmacokinetic interactions between macitentan, a novel endothelin receptor antagonist, and sildenafil in healthy subjects.

Sidharta PN, van Giersbergen PL, Wolzt M, Dingemanse J. Sidharta PN, et al. Among authors: dingemanse j. Br J Clin Pharmacol. 2014 Nov;78(5):1035-42. doi: 10.1111/bcp.12447. Br J Clin Pharmacol. 2014. PMID: 24962473 Free PMC article. Clinical Trial.

6

A new reversible and potent P2Y12 receptor antagonist (ACT-246475): tolerability, pharmacokinetics, and pharmacodynamics in a first-in-man trial.

Baldoni D, Bruderer S, Krause A, Gutierrez M, Gueret P, Astruc B, Dingemanse J. Baldoni D, et al. Among authors: dingemanse j. Clin Drug Investig. 2014 Nov;34(11):807-18. doi: 10.1007/s40261-014-0236-8. Clin Drug Investig. 2014. PMID: 25331625 Clinical Trial.

7

A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects.

Géhin M, Strasser DS, Zisowsky J, Farine H, Groenen PM, Dingemanse J, Sidharta PN. Géhin M, et al. Among authors: dingemanse j. J Clin Pharmacol. 2015 Jul;55(7):787-97. doi: 10.1002/jcph.478. Epub 2015 Mar 30. J Clin Pharmacol. 2015. PMID: 25655470 Clinical Trial.

8

Biocomparison of Three Formulations of the S1P1 Receptor Modulator Ponesimod in Healthy Subjects.

Juif PE, Hoch M, D'Ambrosio D, Dingemanse J. Juif PE, et al. Among authors: dingemanse j. Drugs R D. 2015 Jun;15(2):203-10. doi: 10.1007/s40268-015-0095-7. Drugs R D. 2015. PMID: 25939333 Free PMC article. Clinical Trial.

9

Absolute Bioavailability of Ponesimod, a Selective S1P₁ Receptor Modulator, in Healthy Male Subjects.

Boehler M, Juif PE, Hoch M, Dingemanse J. Boehler M, et al. Among authors: dingemanse j. Eur J Drug Metab Pharmacokinet. 2017 Feb;42(1):129-134. doi: 10.1007/s13318-016-0325-6. Eur J Drug Metab Pharmacokinet. 2017. PMID: 26883438 Clinical Trial.

10

Clinical pharmacology, efficacy, and safety aspects of sphingosine-1-phosphate receptor modulators.

Juif PE, Kraehenbuehl S, Dingemanse J. Juif PE, et al. Among authors: dingemanse j. Expert Opin Drug Metab Toxicol. 2016 Aug;12(8):879-95. doi: 10.1080/17425255.2016.1196188. Epub 2016 Jun 13. Expert Opin Drug Metab Toxicol. 2016. PMID: 27249325 Review.

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