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The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma.
Kaneda A, Seike T, Danjo T, Nakajima T, Otsubo N, Yamaguchi D, Tsuji Y, Hamaguchi K, Yasunaga M, Nishiya Y, Suzuki M, Saito JI, Yatsunami R, Nakamura S, Sekido Y, Mori K. Kaneda A, et al. Among authors: seike t. Am J Cancer Res. 2020 Dec 1;10(12):4399-4415. eCollection 2020. Am J Cancer Res. 2020. PMID: 33415007 Free PMC article.
CD38 is critical for social behaviour by regulating oxytocin secretion.
Jin D, Liu HX, Hirai H, Torashima T, Nagai T, Lopatina O, Shnayder NA, Yamada K, Noda M, Seike T, Fujita K, Takasawa S, Yokoyama S, Koizumi K, Shiraishi Y, Tanaka S, Hashii M, Yoshihara T, Higashida K, Islam MS, Yamada N, Hayashi K, Noguchi N, Kato I, Okamoto H, Matsushima A, Salmina A, Munesue T, Shimizu N, Mochida S, Asano M, Higashida H. Jin D, et al. Among authors: seike t. Nature. 2007 Mar 1;446(7131):41-5. doi: 10.1038/nature05526. Epub 2007 Feb 7. Nature. 2007. PMID: 17287729
A phase II study of zandelisib in patients with relapsed or refractory indolent non-Hodgkin lymphoma: ME-401-K02 study.
Munakata W, Kumode T, Goto H, Fukuhara N, Shimoyama T, Takeuchi M, Kawakita T, Kubo K, Sawa M, Uchida T, Mishima Y, Ichii M, Hanaya M, Matsumoto A, Kuriki M, Seike T, Izutsu K, Ishizawa K. Munakata W, et al. Among authors: seike t. Br J Haematol. 2025 Jan 8. doi: 10.1111/bjh.19994. Online ahead of print. Br J Haematol. 2025. PMID: 39778876
Green upgrading of SPring-8 to produce stable, ultrabrilliant hard X-ray beams.
Tanaka H, Watanabe T, Abe T, Azumi N, Aoki T, Dewa H, Fujita T, Fukami K, Fukui T, Hara T, Hiraiwa T, Imamura K, Inagaki T, Iwai E, Kagamihata A, Kawase M, Kida Y, Kondo C, Maesaka H, Magome T, Masaki M, Masuda T, Matsubara S, Matsui S, Ohshima T, Oishi M, Seike T, Shoji M, Soutome K, Sugimoto T, Suzuki S, Tajima M, Takano S, Tamura K, Tanaka T, Taniuchi T, Taniuchi Y, Togawa K, Tomai T, Ueda Y, Yamaguchi H, Yabashi M, Ishikawa T. Tanaka H, et al. Among authors: seike t. J Synchrotron Radiat. 2024 Nov 1;31(Pt 6):1420-1437. doi: 10.1107/S1600577524008348. Epub 2024 Oct 24. J Synchrotron Radiat. 2024. PMID: 39443835 Free PMC article.
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