Liu H - Search Results

1

Henagliflozin monotherapy in patients with type 2 diabetes inadequately controlled on diet and exercise: A randomized, double-blind, placebo-controlled, phase 3 trial.

Lu J, Fu L, Li Y, Geng J, Qin L, Li P, Zheng H, Sun Z, Li Y, Zhang L, Sun Y, Chen D, Qin G, Lu W, Guo Y, Zhang Y, Liu H, Zhang T, Zou J. Lu J, et al. Among authors: liu h. Diabetes Obes Metab. 2021 May;23(5):1111-1120. doi: 10.1111/dom.14314. Epub 2021 Jan 31. Diabetes Obes Metab. 2021. PMID: 33417292 Clinical Trial.

2

Henagliflozin as add-on therapy to metformin in patients with type 2 diabetes inadequately controlled with metformin: A multicentre, randomized, double-blind, placebo-controlled, phase 3 trial.

Weng J, Zeng L, Zhang Y, Qu S, Wang X, Li P, Fu L, Ma B, Ye S, Sun J, Lu W, Liu Z, Chen D, Cheng Z, Liu H, Zhang T, Zou J. Weng J, et al. Among authors: liu z, liu h. Diabetes Obes Metab. 2021 Aug;23(8):1754-1764. doi: 10.1111/dom.14389. Epub 2021 Apr 14. Diabetes Obes Metab. 2021. PMID: 33769656 Clinical Trial.

3

Characterization and quantitative determination of henagliflozin metabolites in humans.

Chen Z, Li L, Zhan Y, Zhang Y, Liu H, Zou J, Zhong D. Chen Z, et al. Among authors: liu h. J Pharm Biomed Anal. 2021 Jan 5;192:113632. doi: 10.1016/j.jpba.2020.113632. Epub 2020 Sep 28. J Pharm Biomed Anal. 2021. PMID: 33069964

4

Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers.

Chen ZD, Chen Q, Zhu YT, Zhang YF, Zhan Y, Chen XF, Liang X, Jia JY, Yu C, Liu HY, Zou JJ, Liu YM, Zhong DF. Chen ZD, et al. Clin Ther. 2021 Sep;43(9):e264-e273. doi: 10.1016/j.clinthera.2021.07.008. Epub 2021 Aug 6. Clin Ther. 2021. PMID: 34366153 Clinical Trial.

5

Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration.

Zhang YF, Liu YM, Yu C, Wang YT, Zhan Y, Liu HY, Zou JJ, Jia JY, Chen Q, Zhong DF. Zhang YF, et al. Clin Ther. 2021 Feb;43(2):396-409. doi: 10.1016/j.clinthera.2020.12.012. Epub 2021 Jan 14. Clin Ther. 2021. PMID: 33454124 Clinical Trial.

6

Pharmacokinetics and Pharmacodynamics of Henagliflozin, a Sodium Glucose Co-Transporter 2 Inhibitor, in Chinese Patients with Type 2 Diabetes Mellitus.

Yong X, Wen A, Liu X, Liu H, Liu YP, Li N, Hu T, Chen Y, Wang M, Wang L, Dai X, Huang J, Li J, Shen H. Yong X, et al. Among authors: liu x, liu h, liu yp. Clin Drug Investig. 2016 Mar;36(3):195-202. doi: 10.1007/s40261-015-0366-7. Clin Drug Investig. 2016. PMID: 26692004 Clinical Trial.

7

Evaluation of drug-drug interaction between henagliflozin, a novel sodium-glucose co-transporter 2 inhibitor, and metformin in healthy Chinese males.

Wang L, Wu C, Shen L, Liu H, Chen Y, Liu F, Wang Y, Yang J. Wang L, et al. Among authors: liu h, liu f. Xenobiotica. 2016 Aug;46(8):703-8. doi: 10.3109/00498254.2015.1113576. Epub 2015 Nov 26. Xenobiotica. 2016. PMID: 26608671

8

Discovery of novel sulfonamides as potent and selective inhibitors against human and mouse 11β-hydroxysteroid dehydrogenase type 1.

Xia G, Liu L, Xue M, Liu H, Yu J, Li P, Chen Q, Xiong B, Liu X, Shen J. Xia G, et al. Among authors: liu h, liu x, liu l. Mol Cell Endocrinol. 2012 Jul 6;358(1):46-52. doi: 10.1016/j.mce.2012.02.017. Epub 2012 Mar 3. Mol Cell Endocrinol. 2012. PMID: 22410288

9

Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening.

Xia G, Xue M, Liu L, Yu J, Liu H, Li P, Wang J, Li Y, Xiong B, Shen J. Xia G, et al. Among authors: liu h, liu l. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5739-44. doi: 10.1016/j.bmcl.2011.08.019. Epub 2011 Aug 8. Bioorg Med Chem Lett. 2011. PMID: 21873057

10

Design and synthesis of (R)-1-arylsulfonylpiperidine-2-carboxamides as 11β-hydroxysteroid dehydrogenase type 1 inhibitors.

Xia G, Liu L, Liu H, Yu J, Xu Z, Chen Q, Ma C, Li P, Xiong B, Liu X, Shen J. Xia G, et al. Among authors: liu h, liu x, liu l. ChemMedChem. 2013 Apr;8(4):577-81. doi: 10.1002/cmdc.201300022. Epub 2013 Mar 7. ChemMedChem. 2013. PMID: 23471829

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