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Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation.
Giovinazzo D, Bursac B, Sbodio JI, Nalluru S, Vignane T, Snowman AM, Albacarys LM, Sedlak TW, Torregrossa R, Whiteman M, Filipovic MR, Snyder SH, Paul BD. Giovinazzo D, et al. Among authors: snowman am. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2017225118. doi: 10.1073/pnas.2017225118. Proc Natl Acad Sci U S A. 2021. PMID: 33431651 Free PMC article.
Sulfhydration mediates neuroprotective actions of parkin.
Vandiver MS, Paul BD, Xu R, Karuppagounder S, Rao F, Snowman AM, Ko HS, Lee YI, Dawson VL, Dawson TM, Sen N, Snyder SH. Vandiver MS, et al. Among authors: snowman am. Nat Commun. 2013;4:1626. doi: 10.1038/ncomms2623. Nat Commun. 2013. PMID: 23535647 Free PMC article.
The glutathione cycle shapes synaptic glutamate activity.
Sedlak TW, Paul BD, Parker GM, Hester LD, Snowman AM, Taniguchi Y, Kamiya A, Snyder SH, Sawa A. Sedlak TW, et al. Among authors: snowman am. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2701-2706. doi: 10.1073/pnas.1817885116. Epub 2019 Jan 28. Proc Natl Acad Sci U S A. 2019. PMID: 30692251 Free PMC article.
74 results