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Age-Related Decline in Primary CD8+ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8+ T Cells.
Quinn KM, Fox A, Harland KL, Russ BE, Li J, Nguyen THO, Loh L, Olshanksy M, Naeem H, Tsyganov K, Wiede F, Webster R, Blyth C, Sng XYX, Tiganis T, Powell D, Doherty PC, Turner SJ, Kedzierska K, La Gruta NL. Quinn KM, et al. Among authors: la gruta nl. Cell Rep. 2018 Jun 19;23(12):3512-3524. doi: 10.1016/j.celrep.2018.05.057. Cell Rep. 2018. PMID: 29924995 Free article.
MHC Restriction: Where Are We Now?
Zareie P, Farenc C, La Gruta NL. Zareie P, et al. Among authors: la gruta nl. Viral Immunol. 2020 Apr;33(3):179-187. doi: 10.1089/vim.2019.0195. Viral Immunol. 2020. PMID: 32286180 Free PMC article. No abstract available.
The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Lim JJ, Jones CM, Loh TJ, Ting YT, Zareie P, Loh KL, Felix NJ, Suri A, McKinnon M, Stevenaert F, Sharma RK, Klareskog L, Malmström V, Baker DG, Purcell AW, Reid HH, La Gruta NL, Rossjohn J. Lim JJ, et al. Among authors: la gruta nl. Sci Immunol. 2021 Apr 16;6(58):eabe0896. doi: 10.1126/sciimmunol.abe0896. Sci Immunol. 2021. PMID: 33863750
Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
Zareie P, Szeto C, Farenc C, Gunasinghe SD, Kolawole EM, Nguyen A, Blyth C, Sng XYX, Li J, Jones CM, Fulcher AJ, Jacobs JR, Wei Q, Wojciech L, Petersen J, Gascoigne NRJ, Evavold BD, Gaus K, Gras S, Rossjohn J, La Gruta NL. Zareie P, et al. Among authors: la gruta nl. Science. 2021 Jun 4;372(6546):eabe9124. doi: 10.1126/science.abe9124. Science. 2021. PMID: 34083463
Checkpoint inhibitor immunotherapy diminishes oocyte number and quality in mice.
Winship AL, Alesi LR, Sant S, Stringer JM, Cantavenera A, Hegarty T, Requesens CL, Liew SH, Sarma U, Griffiths MJ, Zerafa N, Fox SB, Brown E, Caramia F, Zareie P, La Gruta NL, Phillips KA, Strasser A, Loi S, Hutt KJ. Winship AL, et al. Among authors: la gruta nl. Nat Cancer. 2022 Aug;3(8):1-13. doi: 10.1038/s43018-022-00413-x. Epub 2022 Aug 25. Nat Cancer. 2022. PMID: 36008687
107 results