Hetz C - Search Results

1

Therapeutic potential of insulin-like growth factor 2 in Huntington's disease: controlling proteostasis to alleviate the load of misfolded protein.

Troncoso-Escudero P, Hetz C, Vidal RL. Troncoso-Escudero P, et al. Among authors: hetz c. Neural Regen Res. 2021 Aug;16(8):1564-1565. doi: 10.4103/1673-5374.303020. Neural Regen Res. 2021. PMID: 33433484 Free PMC article. No abstract available.

2

Converging pathways in the occurrence of endoplasmic reticulum (ER) stress in Huntington's disease.

Vidal R, Caballero B, Couve A, Hetz C. Vidal R, et al. Among authors: hetz c. Curr Mol Med. 2011 Feb;11(1):1-12. doi: 10.2174/156652411794474419. Curr Mol Med. 2011. PMID: 21189122 Review.

3

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.

Vidal RL, Figueroa A, Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, Glimcher LH, Hetz C. Vidal RL, et al. Among authors: hetz c. Hum Mol Genet. 2012 May 15;21(10):2245-62. doi: 10.1093/hmg/dds040. Epub 2012 Feb 14. Hum Mol Genet. 2012. PMID: 22337954 Free PMC article.

4

AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease.

Zuleta A, Vidal RL, Armentano D, Parsons G, Hetz C. Zuleta A, et al. Among authors: hetz c. Biochem Biophys Res Commun. 2012 Apr 13;420(3):558-63. doi: 10.1016/j.bbrc.2012.03.033. Epub 2012 Mar 16. Biochem Biophys Res Commun. 2012. PMID: 22445760

5

Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease.

Vidal RL, Hetz C. Vidal RL, et al. Among authors: hetz c. Autophagy. 2012 Jun;8(6):970-2. doi: 10.4161/auto.20139. Epub 2012 May 23. Autophagy. 2012. PMID: 22617512 Free PMC article.

6

Unspliced XBP1 controls autophagy through FoxO1.

Vidal RL, Hetz C. Vidal RL, et al. Among authors: hetz c. Cell Res. 2013 Apr;23(4):463-4. doi: 10.1038/cr.2013.9. Epub 2013 Jan 22. Cell Res. 2013. PMID: 23337584 Free PMC article.

7

Role of the unfolded protein response in organ physiology: lessons from mouse models.

Cornejo VH, Pihán P, Vidal RL, Hetz C. Cornejo VH, et al. Among authors: hetz c. IUBMB Life. 2013 Dec;65(12):962-75. doi: 10.1002/iub.1224. Epub 2013 Nov 13. IUBMB Life. 2013. PMID: 24227223 Free article.

8

A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington's disease in mice.

Acuña AI, Esparza M, Kramm C, Beltrán FA, Parra AV, Cepeda C, Toro CA, Vidal RL, Hetz C, Concha II, Brauchi S, Levine MS, Castro MA. Acuña AI, et al. Among authors: hetz c. Nat Commun. 2013;4:2917. doi: 10.1038/ncomms3917. Nat Commun. 2013. PMID: 24336051 Free PMC article.

9

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1.

Valdés P, Mercado G, Vidal RL, Molina C, Parsons G, Court FA, Martinez A, Galleguillos D, Armentano D, Schneider BL, Hetz C. Valdés P, et al. Among authors: hetz c. Proc Natl Acad Sci U S A. 2014 May 6;111(18):6804-9. doi: 10.1073/pnas.1321845111. Epub 2014 Apr 21. Proc Natl Acad Sci U S A. 2014. PMID: 24753614 Free PMC article.

10

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis.

Nassif M, Valenzuela V, Rojas-Rivera D, Vidal R, Matus S, Castillo K, Fuentealba Y, Kroemer G, Levine B, Hetz C. Nassif M, et al. Among authors: hetz c. Autophagy. 2014 Jul;10(7):1256-71. doi: 10.4161/auto.28784. Epub 2014 May 12. Autophagy. 2014. PMID: 24905722 Free PMC article.

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