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Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity.
Arita M, Watanabe S, Aoki N, Kuwahara S, Suzuki R, Goto S, Abe Y, Takahashi M, Sato M, Hokari S, Ohtsubo A, Shoji S, Nozaki K, Ichikawa K, Kondo R, Hayashi M, Ohshima Y, Kabasawa H, Hosojima M, Koya T, Saito A, Kikuchi T. Arita M, et al. Among authors: goto s. Sci Rep. 2021 Jan 12;11(1):750. doi: 10.1038/s41598-020-80853-6. Sci Rep. 2021. PMID: 33437029 Free PMC article.
Megalin Blockade with Cilastatin Suppresses Drug-Induced Nephrotoxicity.
Hori Y, Aoki N, Kuwahara S, Hosojima M, Kaseda R, Goto S, Iida T, De S, Kabasawa H, Kaneko R, Aoki H, Tanabe Y, Kagamu H, Narita I, Kikuchi T, Saito A. Hori Y, et al. Among authors: goto s. J Am Soc Nephrol. 2017 Jun;28(6):1783-1791. doi: 10.1681/ASN.2016060606. Epub 2017 Jan 4. J Am Soc Nephrol. 2017. PMID: 28052987 Free PMC article.
Rice Endosperm Protein Administration to Juvenile Mice Regulates Gut Microbiota and Suppresses the Development of High-Fat Diet-Induced Obesity and Related Disorders in Adulthood.
Higuchi Y, Hosojima M, Kabasawa H, Kuwahara S, Goto S, Toba K, Kaseda R, Tanaka T, Kitamura N, Takihara H, Okuda S, Taniguchi M, Arao H, Narita I, Saito A. Higuchi Y, et al. Among authors: goto s. Nutrients. 2019 Dec 2;11(12):2919. doi: 10.3390/nu11122919. Nutrients. 2019. PMID: 31810329 Free PMC article.
Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury.
Kawakami R, Matsui M, Konno A, Kaneko R, Shrestha S, Shrestha S, Sunaga H, Hanaoka H, Goto S, Hosojima M, Kabasawa H, Obokata M, Koitabashi N, Matsui H, Sasaki T, Saito A, Yanagita M, Hirai H, Kurabayashi M, Iso T. Kawakami R, et al. Among authors: goto s. J Pathol. 2021 Dec;255(4):362-373. doi: 10.1002/path.5775. Epub 2021 Sep 1. J Pathol. 2021. PMID: 34370295 Free PMC article.
Urinary A- and C-megalin predict progression of diabetic kidney disease: an exploratory retrospective cohort study.
Iida T, Hosojima M, Kabasawa H, Yamamoto-Kabasawa K, Goto S, Tanaka T, Kitamura N, Nakada M, Itoh S, Ogasawara S, Kaseda R, Suzuki Y, Narita I, Saito A. Iida T, et al. Among authors: goto s. J Diabetes Complications. 2022 Nov;36(11):108312. doi: 10.1016/j.jdiacomp.2022.108312. Epub 2022 Sep 24. J Diabetes Complications. 2022. PMID: 36228564 Free article.
The endocytosis receptor megalin: From bench to bedside.
Goto S, Hosojima M, Kabasawa H, Saito A. Goto S, et al. Int J Biochem Cell Biol. 2023 Apr;157:106393. doi: 10.1016/j.biocel.2023.106393. Epub 2023 Feb 28. Int J Biochem Cell Biol. 2023. PMID: 36863658 Free article. Review.
Megalin is involved in angiotensinogen-induced, angiotensin II-mediated ERK1/2 signaling to activate Na + -H + exchanger 3 in proximal tubules.
Goto S, Yoshida Y, Hosojima M, Kuwahara S, Kabasawa H, Aoki H, Iida T, Sawada R, Ugamura D, Yoshizawa Y, Takemoto K, Komochi K, Kobayashi R, Kaseda R, Yaoita E, Nagatoishi S, Narita I, Tsumoto K, Saito A. Goto S, et al. J Hypertens. 2023 Nov 1;41(11):1831-1843. doi: 10.1097/HJH.0000000000003555. Epub 2023 Sep 7. J Hypertens. 2023. PMID: 37682076
3,663 results