Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity.
Arita M, Watanabe S, Aoki N, Kuwahara S, Suzuki R, Goto S, Abe Y, Takahashi M, Sato M, Hokari S, Ohtsubo A, Shoji S, Nozaki K, Ichikawa K, Kondo R, Hayashi M, Ohshima Y, Kabasawa H, Hosojima M, Koya T, Saito A, Kikuchi T.
Arita M, et al. Among authors: hokari s.
Sci Rep. 2021 Jan 12;11(1):750. doi: 10.1038/s41598-020-80853-6.
Sci Rep. 2021.
PMID: 33437029
Free PMC article.