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Page 1
Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity.
Arita M, Watanabe S, Aoki N, Kuwahara S, Suzuki R, Goto S, Abe Y, Takahashi M, Sato M, Hokari S, Ohtsubo A, Shoji S, Nozaki K, Ichikawa K, Kondo R, Hayashi M, Ohshima Y, Kabasawa H, Hosojima M, Koya T, Saito A, Kikuchi T. Arita M, et al. Among authors: kabasawa h. Sci Rep. 2021 Jan 12;11(1):750. doi: 10.1038/s41598-020-80853-6. Sci Rep. 2021. PMID: 33437029 Free PMC article.
Regulation of megalin expression in cultured proximal tubule cells by angiotensin II type 1A receptor- and insulin-mediated signaling cross talk.
Hosojima M, Sato H, Yamamoto K, Kaseda R, Soma T, Kobayashi A, Suzuki A, Kabasawa H, Takeyama A, Ikuyama K, Iino N, Nishiyama A, Thekkumkara TJ, Takeda T, Suzuki Y, Gejyo F, Saito A. Hosojima M, et al. Among authors: kabasawa h. Endocrinology. 2009 Feb;150(2):871-8. doi: 10.1210/en.2008-0886. Epub 2008 Oct 16. Endocrinology. 2009. PMID: 18927221
Megalin is downregulated via LPS-TNF-α-ERK1/2 signaling pathway in proximal tubule cells.
Takeyama A, Sato H, Soma-Nagae T, Kabasawa H, Suzuki A, Yamamoto-Kabasawa K, Hosojima M, Kaneko R, Higuchi F, Kaseda R, Ogasawara S, Narita I, Saito A. Takeyama A, et al. Among authors: kabasawa h. Biochem Biophys Res Commun. 2011 Apr 1;407(1):108-12. doi: 10.1016/j.bbrc.2011.02.118. Epub 2011 Feb 28. Biochem Biophys Res Commun. 2011. PMID: 21371423
Significance of urinary full-length and ectodomain forms of megalin in patients with type 2 diabetes.
Ogasawara S, Hosojima M, Kaseda R, Kabasawa H, Yamamoto-Kabasawa K, Kurosawa H, Sato H, Iino N, Takeda T, Suzuki Y, Narita I, Yamagata K, Tomino Y, Gejyo F, Hirayama Y, Sekine S, Saito A. Ogasawara S, et al. Among authors: kabasawa h. Diabetes Care. 2012 May;35(5):1112-8. doi: 10.2337/dc11-1684. Epub 2012 Mar 12. Diabetes Care. 2012. PMID: 22410816 Free PMC article.
Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet-Induced Kidney Disease.
Kuwahara S, Hosojima M, Kaneko R, Aoki H, Nakano D, Sasagawa T, Kabasawa H, Kaseda R, Yasukawa R, Ishikawa T, Suzuki A, Sato H, Kageyama S, Tanaka T, Kitamura N, Narita I, Komatsu M, Nishiyama A, Saito A. Kuwahara S, et al. Among authors: kabasawa h. J Am Soc Nephrol. 2016 Jul;27(7):1996-2008. doi: 10.1681/ASN.2015020190. Epub 2015 Nov 3. J Am Soc Nephrol. 2016. PMID: 26534923 Free PMC article.
Megalin Blockade with Cilastatin Suppresses Drug-Induced Nephrotoxicity.
Hori Y, Aoki N, Kuwahara S, Hosojima M, Kaseda R, Goto S, Iida T, De S, Kabasawa H, Kaneko R, Aoki H, Tanabe Y, Kagamu H, Narita I, Kikuchi T, Saito A. Hori Y, et al. Among authors: kabasawa h. J Am Soc Nephrol. 2017 Jun;28(6):1783-1791. doi: 10.1681/ASN.2016060606. Epub 2017 Jan 4. J Am Soc Nephrol. 2017. PMID: 28052987 Free PMC article.
[Exosomal biomarkers for kidney disease.].
Hosojima M, Kabasawa H, Kuwahara S, Saito A. Hosojima M, et al. Among authors: kabasawa h. Clin Calcium. 2018;28(2):252-259. Clin Calcium. 2018. PMID: 29371492 Japanese.
123 results