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Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders.
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M. Johmura Y, et al. Among authors: sugimoto m. Science. 2021 Jan 15;371(6526):265-270. doi: 10.1126/science.abb5916. Science. 2021. PMID: 33446552
Elimination of p19ARF-expressing cells enhances pulmonary function in mice.
Hashimoto M, Asai A, Kawagishi H, Mikawa R, Iwashita Y, Kanayama K, Sugimoto K, Sato T, Maruyama M, Sugimoto M. Hashimoto M, et al. Among authors: sugimoto m, sugimoto k. JCI Insight. 2016 Aug 4;1(12):e87732. doi: 10.1172/jci.insight.87732. JCI Insight. 2016. PMID: 27699227 Free PMC article.
Protocol for assessing senescence-associated lung pathologies in mice.
Kawaguchi K, Hashimoto M, Mikawa R, Asai A, Sato T, Sugimoto M. Kawaguchi K, et al. Among authors: sugimoto m. STAR Protoc. 2021 Dec 4;2(4):100993. doi: 10.1016/j.xpro.2021.100993. eCollection 2021 Dec 17. STAR Protoc. 2021. PMID: 34927099 Free PMC article.
Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice.
Suda M, Shimizu I, Katsuumi G, Yoshida Y, Hayashi Y, Ikegami R, Matsumoto N, Yoshida Y, Mikawa R, Katayama A, Wada J, Seki M, Suzuki Y, Iwama A, Nakagami H, Nagasawa A, Morishita R, Sugimoto M, Okuda S, Tsuchida M, Ozaki K, Nakanishi-Matsui M, Minamino T. Suda M, et al. Among authors: sugimoto m. Nat Aging. 2021 Dec;1(12):1117-1126. doi: 10.1038/s43587-021-00151-2. Epub 2021 Dec 10. Nat Aging. 2021. PMID: 37117524
2,383 results