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Phase II clinical trial with metronomic oral vinorelbine and tri-weekly cisplatin as induction therapy, subsequently concomitant with radiotherapy (RT) in patients with locally advanced, unresectable, non-small cell lung cancer (NSCLC). Analysis of survival and value of ctDNA for patient selection.
Provencio M, Majem M, Guirado M, Massuti B, de Las Peñas R, Ortega AL, Dómine M, Marsé R, Sala MÁ, Paredes A, Morán T, Vázquez S, Coves J, Larriba JLG, Sánchez JM, Vicente D, Farré N, Fornos LF, Zapata I, Franco F, Serna-Blasco R, Romero A, Isla D. Provencio M, et al. Among authors: romero a. Lung Cancer. 2021 Mar;153:25-34. doi: 10.1016/j.lungcan.2021.01.005. Epub 2021 Jan 10. Lung Cancer. 2021. PMID: 33453470 Clinical Trial.
Comparison of methods for circulating cell-free DNA isolation using blood from cancer patients: impact on biomarker testing.
Pérez-Barrios C, Nieto-Alcolado I, Torrente M, Jiménez-Sánchez C, Calvo V, Gutierrez-Sanz L, Palka M, Donoso-Navarro E, Provencio M, Romero A. Pérez-Barrios C, et al. Among authors: romero a. Transl Lung Cancer Res. 2016 Dec;5(6):665-672. doi: 10.21037/tlcr.2016.12.03. Transl Lung Cancer Res. 2016. PMID: 28149760 Free PMC article.
Tumor burden monitoring using cell-free tumor DNA could be limited by tumor heterogeneity in advanced breast cancer and should be evaluated together with radiographic imaging.
García-Saenz JA, Ayllón P, Laig M, Acosta-Eyzaguirre D, García-Esquinas M, Montes M, Sanz J, Barquín M, Moreno F, Garcia-Barberan V, Díaz-Rubio E, Caldes T, Romero A. García-Saenz JA, et al. Among authors: romero a. BMC Cancer. 2017 Mar 22;17(1):210. doi: 10.1186/s12885-017-3185-9. BMC Cancer. 2017. PMID: 28330468 Free PMC article.
Concordance between circulating tumor cells and clinical status during follow-up in anaplastic lymphoma kinase (ALK) non-small-cell lung cancer patients.
Provencio M, Pérez-Callejo D, Torrente M, Martin P, Calvo V, Gutiérrez L, Franco F, Coronado MJ, Cruz-Bermúdez JL, Ruiz-Valdepeñas AM, Cruz-Bermúdez A, Sánchez-Beato M, Romero A, García-Grande A. Provencio M, et al. Among authors: romero a. Oncotarget. 2017 Jul 31;8(35):59408-59416. doi: 10.18632/oncotarget.19722. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938646 Free PMC article.
Dynamic circulating tumor DNA quantificaton for the individualization of non-small-cell lung cancer patients treatment.
Provencio M, Torrente M, Calvo V, Gutiérrez L, Pérez-Callejo D, Pérez-Barrios C, Barquín M, Royuela A, Rodriguez-Alfonso B, Sotelo M, Cruz-Bermúdez JL, Mendez M, Cruz-Bermúdez A, Romero A. Provencio M, et al. Among authors: romero a. Oncotarget. 2017 Aug 7;8(36):60291-60298. doi: 10.18632/oncotarget.20016. eCollection 2017 Sep 1. Oncotarget. 2017. PMID: 28947971 Free PMC article.
PGC-1alpha levels correlate with survival in patients with stage III NSCLC and may define a new biomarker to metabolism-targeted therapy.
Cruz-Bermúdez A, Vicente-Blanco RJ, Laza-Briviesca R, García-Grande A, Laine-Menéndez S, Gutiérrez L, Calvo V, Romero A, Martín-Acosta P, García JM, Provencio M. Cruz-Bermúdez A, et al. Among authors: romero a. Sci Rep. 2017 Nov 30;7(1):16661. doi: 10.1038/s41598-017-17009-6. Sci Rep. 2017. PMID: 29192176 Free PMC article.
Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients.
Provencio M, Torrente M, Calvo V, Pérez-Callejo D, Gutiérrez L, Franco F, Pérez-Barrios C, Barquín M, Royuela A, García-García F, Bueno C, Garcia-Grande A, Camps C, Massuti B, Sotomayor E, Romero A. Provencio M, et al. Among authors: romero a. Oncotarget. 2017 Nov 16;9(1):488-494. doi: 10.18632/oncotarget.22470. eCollection 2018 Jan 2. Oncotarget. 2017. PMID: 29416630 Free PMC article.
Cancer-associated fibroblasts modify lung cancer metabolism involving ROS and TGF-β signaling.
Cruz-Bermúdez A, Laza-Briviesca R, Vicente-Blanco RJ, García-Grande A, Coronado MJ, Laine-Menéndez S, Alfaro C, Sanchez JC, Franco F, Calvo V, Romero A, Martin-Acosta P, Salas C, Garcia JM, Provencio M. Cruz-Bermúdez A, et al. Among authors: romero a. Free Radic Biol Med. 2019 Jan;130:163-173. doi: 10.1016/j.freeradbiomed.2018.10.450. Epub 2018 Nov 1. Free Radic Biol Med. 2019. PMID: 30391585 Free article.
2,340 results