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Page 1
Characterization of RA839, a Noncovalent Small Molecule Binder to Keap1 and Selective Activator of Nrf2 Signaling.
Winkel AF, Engel CK, Margerie D, Kannt A, Szillat H, Glombik H, Kallus C, Ruf S, Güssregen S, Riedel J, Herling AW, von Knethen A, Weigert A, Brüne B, Schmoll D. Winkel AF, et al. Among authors: kannt a. J Biol Chem. 2015 Nov 20;290(47):28446-28455. doi: 10.1074/jbc.M115.678136. Epub 2015 Oct 12. J Biol Chem. 2015. PMID: 26459563 Free PMC article.
Activation of Adenosine Monophosphate-Activated Protein Kinase Reduces the Onset of Diet-Induced Hepatocellular Carcinoma in Mice.
Schmoll D, Ziegler N, Viollet B, Foretz M, Even PC, Azzout-Marniche D, Nygaard Madsen A, Illemann M, Mandrup K, Feigh M, Czech J, Glombik H, Olsen JA, Hennerici W, Steinmeyer K, Elvert R, Castañeda TR, Kannt A. Schmoll D, et al. Among authors: kannt a. Hepatol Commun. 2020 May 15;4(7):1056-1072. doi: 10.1002/hep4.1508. eCollection 2020 Jul. Hepatol Commun. 2020. PMID: 32626837 Free PMC article.
Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis.
Mishra A, Castañeda TR, Bader E, Elshorst B, Cummings S, Scherer P, Bangari DS, Loewe C, Schreuder H, Pöverlein C, Helms M, Jones S, Zech G, Licher T, Wagner M, Schudok M, de Hoop M, Plowright AT, Atzrodt J, Kannt A, Laitinen I, Derdau V. Mishra A, et al. Among authors: kannt a. Adv Sci (Weinh). 2020 Nov 9;7(24):2002997. doi: 10.1002/advs.202002997. eCollection 2020 Dec. Adv Sci (Weinh). 2020. PMID: 33344141 Free PMC article.
Novel β-amino acid derivatives as inhibitors of cathepsin A.
Ruf S, Buning C, Schreuder H, Horstick G, Linz W, Olpp T, Pernerstorfer J, Hiss K, Kroll K, Kannt A, Kohlmann M, Linz D, Hübschle T, Rütten H, Wirth K, Schmidt T, Sadowski T. Ruf S, et al. Among authors: kannt a. J Med Chem. 2012 Sep 13;55(17):7636-49. doi: 10.1021/jm300663n. Epub 2012 Aug 16. J Med Chem. 2012. PMID: 22861813
Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.
Ruf S, Hallur MS, Anchan NK, Swamy IN, Murugesan KR, Sarkar S, Narasimhulu LK, Putta VPRK, Shaik S, Chandrasekar DV, Mane VS, Kadnur SV, Suresh J, Bhamidipati RK, Singh M, Burri RR, Kristam R, Schreuder H, Czech J, Rudolph C, Marker A, Langer T, Mullangi R, Yura T, Gosu R, Kannt A, Dhakshinamoorthy S, Rajagopal S. Ruf S, et al. Among authors: kannt a. Bioorg Med Chem Lett. 2018 Mar 1;28(5):922-925. doi: 10.1016/j.bmcl.2018.01.058. Epub 2018 Jan 31. Bioorg Med Chem Lett. 2018. PMID: 29433927
High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT).
Policarpo RL, Decultot L, May E, Kuzmič P, Carlson S, Huang D, Chu V, Wright BA, Dhakshinamoorthy S, Kannt A, Rani S, Dittakavi S, Panarese JD, Gaudet R, Shair MD. Policarpo RL, et al. Among authors: kannt a. J Med Chem. 2019 Nov 14;62(21):9837-9873. doi: 10.1021/acs.jmedchem.9b01238. Epub 2019 Oct 25. J Med Chem. 2019. PMID: 31589440 Free PMC article.
73 results