Haataja L - Search Results

1

Normal and defective pathways in biogenesis and maintenance of the insulin storage pool.

Liu M, Huang Y, Xu X, Li X, Alam M, Arunagiri A, Haataja L, Ding L, Wang S, Itkin-Ansari P, Kaufman RJ, Tsai B, Qi L, Arvan P. Liu M, et al. Among authors: haataja l. J Clin Invest. 2021 Jan 19;131(2):e142240. doi: 10.1172/JCI142240. J Clin Invest. 2021. PMID: 33463547 Free PMC article. Review.

2

Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.

Liu M, Hodish I, Haataja L, Lara-Lemus R, Rajpal G, Wright J, Arvan P. Liu M, et al. Among authors: haataja l. Trends Endocrinol Metab. 2010 Nov;21(11):652-9. doi: 10.1016/j.tem.2010.07.001. Epub 2010 Aug 18. Trends Endocrinol Metab. 2010. PMID: 20724178 Free PMC article. Review.

3

Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.

Liu M, Haataja L, Wright J, Wickramasinghe NP, Hua QX, Phillips NF, Barbetti F, Weiss MA, Arvan P. Liu M, et al. Among authors: haataja l. PLoS One. 2010 Oct 11;5(10):e13333. doi: 10.1371/journal.pone.0013333. PLoS One. 2010. PMID: 20948967 Free PMC article.

4

In vivo misfolding of proinsulin below the threshold of frank diabetes.

Hodish I, Absood A, Liu L, Liu M, Haataja L, Larkin D, Al-Khafaji A, Zaki A, Arvan P. Hodish I, et al. Among authors: haataja l. Diabetes. 2011 Aug;60(8):2092-101. doi: 10.2337/db10-1671. Epub 2011 Jun 15. Diabetes. 2011. PMID: 21677281 Free PMC article.

5

Impaired cleavage of preproinsulin signal peptide linked to autosomal-dominant diabetes.

Liu M, Lara-Lemus R, Shan SO, Wright J, Haataja L, Barbetti F, Guo H, Larkin D, Arvan P. Liu M, et al. Among authors: haataja l. Diabetes. 2012 Apr;61(4):828-37. doi: 10.2337/db11-0878. Epub 2012 Feb 22. Diabetes. 2012. PMID: 22357960 Free PMC article.

6

Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cells.

Haataja L, Snapp E, Wright J, Liu M, Hardy AB, Wheeler MB, Markwardt ML, Rizzo MA, Arvan P. Haataja L, et al. J Biol Chem. 2013 Jan 18;288(3):1896-906. doi: 10.1074/jbc.M112.420018. Epub 2012 Dec 6. J Biol Chem. 2013. PMID: 23223446 Free PMC article.

7

Dominant protein interactions that influence the pathogenesis of conformational diseases.

Wright J, Wang X, Haataja L, Kellogg AP, Lee J, Liu M, Arvan P. Wright J, et al. Among authors: haataja l. J Clin Invest. 2013 Jul;123(7):3124-34. doi: 10.1172/JCI67260. Epub 2013 Jun 3. J Clin Invest. 2013. PMID: 23722904 Free PMC article.

8

Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.

Wright J, Birk J, Haataja L, Liu M, Ramming T, Weiss MA, Appenzeller-Herzog C, Arvan P. Wright J, et al. Among authors: haataja l. J Biol Chem. 2013 Oct 25;288(43):31010-8. doi: 10.1074/jbc.M113.510065. Epub 2013 Sep 10. J Biol Chem. 2013. PMID: 24022479 Free PMC article.

9

Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes.

Guo H, Xiong Y, Witkowski P, Cui J, Wang LJ, Sun J, Lara-Lemus R, Haataja L, Hutchison K, Shan SO, Arvan P, Liu M. Guo H, et al. Among authors: haataja l. J Biol Chem. 2014 Jun 6;289(23):16290-302. doi: 10.1074/jbc.M114.562355. Epub 2014 Apr 25. J Biol Chem. 2014. PMID: 24770419 Free PMC article.

10

Sox17 regulates insulin secretion in the normal and pathologic mouse β cell.

Jonatan D, Spence JR, Method AM, Kofron M, Sinagoga K, Haataja L, Arvan P, Deutsch GH, Wells JM. Jonatan D, et al. Among authors: haataja l. PLoS One. 2014 Aug 21;9(8):e104675. doi: 10.1371/journal.pone.0104675. eCollection 2014. PLoS One. 2014. PMID: 25144761 Free PMC article.

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