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Resistance to pirimiphos-methyl in West African Anopheles is spreading via duplication and introgression of the Ace1 locus.
Grau-Bové X, Lucas E, Pipini D, Rippon E, van 't Hof AE, Constant E, Dadzie S, Egyir-Yawson A, Essandoh J, Chabi J, Djogbénou L, Harding NJ, Miles A, Kwiatkowski D, Donnelly MJ, Weetman D; Anopheles gambiae 1000 Genomes Consortium. Grau-Bové X, et al. Among authors: kwiatkowski d. PLoS Genet. 2021 Jan 21;17(1):e1009253. doi: 10.1371/journal.pgen.1009253. eCollection 2021 Jan. PLoS Genet. 2021. PMID: 33476334 Free PMC article.
Population genomics reveal distinct and diverging populations of An. minimus in Cambodia.
St Laurent B, Harding N, Deason N, Oy K, Sok Loeun C, Sary M, Sunly R, Nhep S, Drury E, Rockett K, Sovannaroth S, Goncalves S, Kwiatkowski D, Miles A. St Laurent B, et al. Among authors: kwiatkowski d. Commun Biol. 2022 Nov 28;5(1):1308. doi: 10.1038/s42003-022-04259-y. Commun Biol. 2022. PMID: 36443434 Free PMC article.
Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii.
Lucas ER, Nagi SC, Egyir-Yawson A, Essandoh J, Dadzie S, Chabi J, Djogbénou LS, Medjigbodo AA, Edi CV, Kétoh GK, Koudou BG, Van't Hof AE, Rippon EJ, Pipini D, Harding NJ, Dyer NA, Cerdeira LT, Clarkson CS, Kwiatkowski DP, Miles A, Donnelly MJ, Weetman D. Lucas ER, et al. Among authors: kwiatkowski dp. Nat Commun. 2023 Aug 16;14(1):4946. doi: 10.1038/s41467-023-40693-0. Nat Commun. 2023. PMID: 37587104 Free PMC article.
Resistance to malaria through structural variation of red blood cell invasion receptors.
Leffler EM, Band G, Busby GBJ, Kivinen K, Le QS, Clarke GM, Bojang KA, Conway DJ, Jallow M, Sisay-Joof F, Bougouma EC, Mangano VD, Modiano D, Sirima SB, Achidi E, Apinjoh TO, Marsh K, Ndila CM, Peshu N, Williams TN, Drakeley C, Manjurano A, Reyburn H, Riley E, Kachala D, Molyneux M, Nyirongo V, Taylor T, Thornton N, Tilley L, Grimsley S, Drury E, Stalker J, Cornelius V, Hubbart C, Jeffreys AE, Rowlands K, Rockett KA, Spencer CCA, Kwiatkowski DP; Malaria Genomic Epidemiology Network. Leffler EM, et al. Among authors: kwiatkowski dp. Science. 2017 Jun 16;356(6343):eaam6393. doi: 10.1126/science.aam6393. Epub 2017 May 18. Science. 2017. PMID: 28522690 Free PMC article.
Major subpopulations of Plasmodium falciparum in sub-Saharan Africa.
Amambua-Ngwa A, Amenga-Etego L, Kamau E, Amato R, Ghansah A, Golassa L, Randrianarivelojosia M, Ishengoma D, Apinjoh T, Maïga-Ascofaré O, Andagalu B, Yavo W, Bouyou-Akotet M, Kolapo O, Mane K, Worwui A, Jeffries D, Simpson V, D'Alessandro U, Kwiatkowski D, Djimde AA. Amambua-Ngwa A, et al. Among authors: kwiatkowski d, d alessandro u. Science. 2019 Aug 23;365(6455):813-816. doi: 10.1126/science.aav5427. Science. 2019. PMID: 31439796
An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples.
MalariaGEN; Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amato R, Amenga-Etego L, Andagalu B, Anderson TJC, Andrianaranjaka V, Apinjoh T, Ariani C, Ashley EA, Auburn S, Awandare GA, Ba H, Baraka V, Barry AE, Bejon P, Bertin GI, Boni MF, Borrmann S, Bousema T, Branch O, Bull PC, Busby GBJ, Chookajorn T, Chotivanich K, Claessens A, Conway D, Craig A, D'Alessandro U, Dama S, Day NP, Denis B, Diakite M, Djimdé A, Dolecek C, Dondorp AM, Drakeley C, Drury E, Duffy P, Echeverry DF, Egwang TG, Erko B, Fairhurst RM, Faiz A, Fanello CA, Fukuda MM, Gamboa D, Ghansah A, Golassa L, Goncalves S, Hamilton WL, Harrison GLA, Hart L, Henrichs C, Hien TT, Hill CA, Hodgson A, Hubbart C, Imwong M, Ishengoma DS, Jackson SA, Jacob CG, Jeffery B, Jeffreys AE, Johnson KJ, Jyothi D, Kamaliddin C, Kamau E, Kekre M, Kluczynski K, Kochakarn T, Konaté A, Kwiatkowski DP, Kyaw MP, Lim P, Lon C, Loua KM, Maïga-Ascofaré O, Malangone C, Manske M, Marfurt J, Marsh K, Mayxay M, Miles A, Miotto O, Mobegi V, Mokuolu OA, Montgomery J, Mueller I, Newton PN, Nguyen T, Nguyen TN, Noedl H, Nosten F, Noviyanti R, Nzila A, Ochola-Oyier LI, Ocholla H, Oduro A, Omedo I, Onyamboko MA, Ouedraogo… See abstract for full author list ➔ MalariaGEN, et al. Among authors: kwiatkowski dp, d alessandro u. Wellcome Open Res. 2021 Jul 13;6:42. doi: 10.12688/wellcomeopenres.16168.2. eCollection 2021. Wellcome Open Res. 2021. PMID: 33824913 Free PMC article.
A targeted amplicon sequencing panel to simultaneously identify mosquito species and Plasmodium presence across the entire Anopheles genus.
Makunin A, Korlević P, Park N, Goodwin S, Waterhouse RM, von Wyschetzki K, Jacob CG, Davies R, Kwiatkowski D, St Laurent B, Ayala D, Lawniczak MKN. Makunin A, et al. Among authors: kwiatkowski d. Mol Ecol Resour. 2022 Jan;22(1):28-44. doi: 10.1111/1755-0998.13436. Epub 2021 Jun 19. Mol Ecol Resour. 2022. PMID: 34053186 Free PMC article.
1,032 results