Wells JA - Search Results

1

Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy.

Chen W, Mou KY, Solomon P, Aggarwal R, Leung KK, Wells JA. Chen W, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2018861118. doi: 10.1073/pnas.2018861118. Proc Natl Acad Sci U S A. 2021. PMID: 33483421 Free PMC article.

2

A common allosteric site and mechanism in caspases.

Scheer JM, Romanowski MJ, Wells JA. Scheer JM, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7595-600. doi: 10.1073/pnas.0602571103. Epub 2006 May 8. Proc Natl Acad Sci U S A. 2006. PMID: 16682620 Free PMC article.

3

Two-state selection of conformation-specific antibodies.

Gao J, Sidhu SS, Wells JA. Gao J, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3071-6. doi: 10.1073/pnas.0812952106. Epub 2009 Feb 10. Proc Natl Acad Sci U S A. 2009. PMID: 19208804 Free PMC article.

4

Sampling the N-terminal proteome of human blood.

Wildes D, Wells JA. Wildes D, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4561-6. doi: 10.1073/pnas.0914495107. Epub 2010 Feb 19. Proc Natl Acad Sci U S A. 2010. PMID: 20173099 Free PMC article.

5

Turning a protein kinase on or off from a single allosteric site via disulfide trapping.

Sadowsky JD, Burlingame MA, Wolan DW, McClendon CL, Jacobson MP, Wells JA. Sadowsky JD, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6056-61. doi: 10.1073/pnas.1102376108. Epub 2011 Mar 23. Proc Natl Acad Sci U S A. 2011. PMID: 21430264 Free PMC article.

6

Global kinetic analysis of proteolysis via quantitative targeted proteomics.

Agard NJ, Mahrus S, Trinidad JC, Lynn A, Burlingame AL, Wells JA. Agard NJ, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1913-8. doi: 10.1073/pnas.1117158109. Epub 2012 Jan 23. Proc Natl Acad Sci U S A. 2012. PMID: 22308409 Free PMC article.

7

Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis.

Shimbo K, Hsu GW, Nguyen H, Mahrus S, Trinidad JC, Burlingame AL, Wells JA. Shimbo K, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12432-7. doi: 10.1073/pnas.1208616109. Epub 2012 Jul 16. Proc Natl Acad Sci U S A. 2012. PMID: 22802652 Free PMC article.

8

Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation.

Thomsen ND, Koerber JT, Wells JA. Thomsen ND, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8477-82. doi: 10.1073/pnas.1306759110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650375 Free PMC article.

9

Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling.

Wiita AP, Hsu GW, Lu CM, Esensten JH, Wells JA. Wiita AP, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7594-9. doi: 10.1073/pnas.1405987111. Epub 2014 May 12. Proc Natl Acad Sci U S A. 2014. PMID: 24821784 Free PMC article.

10

A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.

Rettenmaier TJ, Sadowsky JD, Thomsen ND, Chen SC, Doak AK, Arkin MR, Wells JA. Rettenmaier TJ, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18590-5. doi: 10.1073/pnas.1415365112. Epub 2014 Dec 17. Proc Natl Acad Sci U S A. 2014. PMID: 25518860 Free PMC article.

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