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Prolonged dopamine D3 receptor stimulation promotes dopamine transporter ubiquitination and degradation through a PKC-dependent mechanism.
Luis-Ravelo D, Fumagallo-Reading F, Castro-Hernandez J, Barroso-Chinea P, Afonso-Oramas D, Febles-Casquero A, Cruz-Muros I, Salas-Hernandez J, Mesa-Infante V, Rodriguez-Nuñez J, Gonzalez-Hernandez T. Luis-Ravelo D, et al. Among authors: mesa infante v. Pharmacol Res. 2021 Mar;165:105434. doi: 10.1016/j.phrs.2021.105434. Epub 2021 Jan 20. Pharmacol Res. 2021. PMID: 33484816
Oxidative stress induced by sustained supraphysiological intrastriatal GDNF delivery is prevented by dose regulation.
Azevedo MD, Prince N, Humbert-Claude M, Mesa-Infante V, Jeanneret C, Golzne V, De Matos K, Jamot BB, Magara F, Gonzalez-Hernandez T, Tenenbaum L. Azevedo MD, et al. Among authors: mesa infante v. Mol Ther Methods Clin Dev. 2023 Sep 9;31:101106. doi: 10.1016/j.omtm.2023.09.002. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 37766790 Free PMC article.