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Page 1
Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients.
Kuno R, Ito G, Kawamoto A, Hiraguri Y, Sugihara HY, Takeoka S, Nagata S, Takahashi J, Tsuchiya M, Anzai S, Mizutani T, Shimizu H, Yui S, Oshima S, Tsuchiya K, Watanabe M, Okamoto R. Kuno R, et al. Among authors: sugihara hy. Biochem Biophys Rep. 2021 Jan 11;25:100906. doi: 10.1016/j.bbrep.2020.100906. eCollection 2021 Mar. Biochem Biophys Rep. 2021. PMID: 33490652 Free PMC article.
Organoid-based regenerative medicine for inflammatory bowel disease.
Okamoto R, Shimizu H, Suzuki K, Kawamoto A, Takahashi J, Kawai M, Nagata S, Hiraguri Y, Takeoka S, Sugihara HY, Yui S, Watanabe M. Okamoto R, et al. Among authors: sugihara hy. Regen Ther. 2020 Jan 13;13:1-6. doi: 10.1016/j.reth.2019.11.004. eCollection 2020 Mar. Regen Ther. 2020. PMID: 31970266 Free PMC article. Review.
TGF-β promotes fetal gene expression and cell migration velocity in a wound repair model of untransformed intestinal epithelial cells.
Anzai S, Kawamoto A, Nagata S, Takahashi J, Kawai M, Kuno R, Kobayashi S, Watanabe S, Suzuki K, Shimizu H, Hiraguri Y, Takeoka S, Sugihara HY, Yui S, Oshima S, Watanabe M, Okamoto R. Anzai S, et al. Among authors: sugihara hy. Biochem Biophys Res Commun. 2020 Apr 9;524(3):533-541. doi: 10.1016/j.bbrc.2020.01.108. Epub 2020 Feb 1. Biochem Biophys Res Commun. 2020. PMID: 32014254
Functional analysis of isoflavones using patient-derived human colonic organoids.
Tsuchiya M, Ito G, Hama M, Nagata S, Kawamoto A, Suzuki K, Shimizu H, Anzai S, Takahashi J, Kuno R, Takeoka S, Hiraguri Y, Sugihara HY, Mizutani T, Yui S, Oshima S, Tsuchiya K, Watanabe M, Okamoto R. Tsuchiya M, et al. Among authors: sugihara hy. Biochem Biophys Res Commun. 2021 Jan 20;542:40-47. doi: 10.1016/j.bbrc.2021.01.021. Online ahead of print. Biochem Biophys Res Commun. 2021. PMID: 33486190
Intestinal organoids: The path towards clinical application.
Sugihara HY, Okamoto R, Mizutani T. Sugihara HY, et al. Eur J Cell Biol. 2024 Dec 25;104(1):151474. doi: 10.1016/j.ejcb.2024.151474. Online ahead of print. Eur J Cell Biol. 2024. PMID: 39740324 Free article.