Takai K - Search Results

1

Analysis of Thermal Behavior of Crystalline Minerals in Bituminous Coal Samples under Air and Argon Atmospheres.

Hashimoto T, Takai K, Nguyen HVQ, Nomura M, Ishihara A. Hashimoto T, et al. Among authors: takai k. ACS Omega. 2021 Jan 5;6(2):1197-1204. doi: 10.1021/acsomega.0c04311. eCollection 2021 Jan 19. ACS Omega. 2021. PMID: 33490778 Free PMC article.

2

Discovery of novel N-substituted oxindoles as selective m1 and m4 muscarinic acetylcholine receptors partial agonists.

Sumiyoshi T, Enomoto T, Takai K, Takahashi Y, Konishi Y, Uruno Y, Tojo K, Suwa A, Matsuda H, Nakako T, Sakai M, Kitamura A, Uematsu Y, Kiyoshi A. Sumiyoshi T, et al. Among authors: takai k. ACS Med Chem Lett. 2013 Jan 27;4(2):244-8. doi: 10.1021/ml300372f. eCollection 2013 Feb 14. ACS Med Chem Lett. 2013. PMID: 24900656 Free PMC article.

3

Identification of N-substituted 8-azatetrahydroquinolone derivatives as selective and orally active M(1) and M(4) muscarinic acetylcholine receptors agonists.

Takai K, Inoue Y, Konishi Y, Suwa A, Uruno Y, Matsuda H, Nakako T, Sakai M, Nishikawa H, Hashimoto G, Enomoto T, Kitamura A, Uematsu Y, Kiyoshi A, Sumiyoshi T. Takai K, et al. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4644-7. doi: 10.1016/j.bmcl.2013.06.013. Epub 2013 Jun 13. Bioorg Med Chem Lett. 2013. PMID: 23816371

4

Discovery of N-sulfonyl-7-azaindoline derivatives as potent, orally available and selective M(4) muscarinic acetylcholine receptor agonists.

Suwa A, Konishi Y, Uruno Y, Takai K, Nakako T, Sakai M, Enomoto T, Ochi Y, Matsuda H, Kitamura A, Uematsu Y, Kiyoshi A, Sumiyoshi T. Suwa A, et al. Among authors: takai k. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2909-12. doi: 10.1016/j.bmcl.2014.04.083. Epub 2014 May 9. Bioorg Med Chem Lett. 2014. PMID: 24852118

5

Discovery of N-substituted 7-azaindoline derivatives as potent, orally available M1 and M4 muscarinic acetylcholine receptors selective agonists.

Takai K, Inoue Y, Konishi Y, Suwa A, Uruno Y, Matsuda H, Nakako T, Sakai M, Nishikawa H, Hashimoto G, Enomoto T, Kitamura A, Uematsu Y, Kiyoshi A, Sumiyoshi T. Takai K, et al. Bioorg Med Chem Lett. 2014 Jul 15;24(14):3189-93. doi: 10.1016/j.bmcl.2014.04.085. Epub 2014 May 10. Bioorg Med Chem Lett. 2014. PMID: 24856064

6

Discovery of dihydroquinazolinone derivatives as potent, selective, and CNS-penetrant M(1) and M(4) muscarinic acetylcholine receptors agonists.

Uruno Y, Konishi Y, Suwa A, Takai K, Tojo K, Nakako T, Sakai M, Enomoto T, Matsuda H, Kitamura A, Sumiyoshi T. Uruno Y, et al. Among authors: takai k. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5357-61. doi: 10.1016/j.bmcl.2015.09.032. Epub 2015 Sep 12. Bioorg Med Chem Lett. 2015. PMID: 26428869

7

Discovery and Development of Muscarinic Acetylcholine M₄ Activators as Promising Therapeutic Agents for CNS Diseases.

Takai K, Enomoto T. Takai K, et al. Chem Pharm Bull (Tokyo). 2018;66(1):37-44. doi: 10.1248/cpb.c17-00413. Chem Pharm Bull (Tokyo). 2018. PMID: 29311510 Free article. Review.

8

Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors.

Takai K, Chiyo N, Nakajima T, Nariai T, Ishikawa C, Nakatani S, Ikeno A, Yamamoto S, Sone T. Takai K, et al. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1705-1708. doi: 10.1016/j.bmcl.2015.02.076. Epub 2015 Mar 7. Bioorg Med Chem Lett. 2015. PMID: 25800114

9

Structure-based optimization of cyclopropyl urea derivatives as potent soluble epoxide hydrolase inhibitors for potential decrease of renal injury without hypotensive action.

Takai K, Nakajima T, Takanashi Y, Sone T, Nariai T, Chiyo N, Nakatani S, Ishikawa C, Yamaguchi N, Fujita K, Yamada K. Takai K, et al. Bioorg Med Chem. 2014 Mar 1;22(5):1548-57. doi: 10.1016/j.bmc.2014.01.040. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24530032

10

The Auditory Steady-State Response: Electrophysiological Index for Sensory Processing Dysfunction in Psychiatric Disorders.

Sugiyama S, Ohi K, Kuramitsu A, Takai K, Muto Y, Taniguchi T, Kinukawa T, Takeuchi N, Motomura E, Nishihara M, Shioiri T, Inui K. Sugiyama S, et al. Among authors: takai k. Front Psychiatry. 2021 Mar 11;12:644541. doi: 10.3389/fpsyt.2021.644541. eCollection 2021. Front Psychiatry. 2021. PMID: 33776820 Free PMC article. Review.

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