Wang L - Search Results

1

Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties.

Jiang B, Luo J, Guo S, Wang L. Jiang B, et al. Among authors: wang l. Bioorg Chem. 2021 Mar;108:104648. doi: 10.1016/j.bioorg.2021.104648. Epub 2021 Jan 12. Bioorg Chem. 2021. PMID: 33493928

2

Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.

Luo J, Xu Q, Jiang B, Zhang R, Jia X, Li X, Wang L, Guo C, Wu N, Shi D. Luo J, et al. Among authors: wang l. Br J Pharmacol. 2018 Jan;175(1):140-153. doi: 10.1111/bph.14080. Epub 2017 Dec 8. Br J Pharmacol. 2018. PMID: 29059712 Free PMC article.

3

Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors.

Li X, Xu Q, Li C, Luo J, Li X, Wang L, Jiang B, Shi D. Li X, et al. Among authors: wang l. Eur J Med Chem. 2019 Mar 15;166:178-185. doi: 10.1016/j.ejmech.2019.01.057. Epub 2019 Jan 25. Eur J Med Chem. 2019. PMID: 30711829

4

Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides.

Luo J, Zheng M, Jiang B, Li C, Guo S, Wang L, Li X, Yu R, Shi D. Luo J, et al. Among authors: wang l. Br J Pharmacol. 2020 Oct;177(19):4464-4480. doi: 10.1111/bph.15195. Epub 2020 Aug 30. Br J Pharmacol. 2020. PMID: 32663313 Free PMC article.

5

Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition.

Luo J, Wu N, Jiang B, Wang L, Wang S, Li X, Wang B, Wang C, Shi D. Luo J, et al. Among authors: wang l, wang s, wang c, wang b. Mar Drugs. 2015 Jul 17;13(7):4452-69. doi: 10.3390/md13074452. Mar Drugs. 2015. PMID: 26193288 Free PMC article.

6

Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors.

Zhang R, Yu R, Xu Q, Li X, Luo J, Jiang B, Wang L, Guo S, Wu N, Shi D. Zhang R, et al. Among authors: wang l. Eur J Med Chem. 2017 Jul 7;134:24-33. doi: 10.1016/j.ejmech.2017.04.004. Epub 2017 Apr 4. Eur J Med Chem. 2017. PMID: 28395151

7

Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity.

Zhang R, Song L, Jiang B, Wang L, Wu N, Guo S, Shi D. Zhang R, et al. Among authors: wang l. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2488-2492. doi: 10.1016/j.bmcl.2017.03.094. Epub 2017 Apr 2. Bioorg Med Chem Lett. 2017. PMID: 28462838

8

A novel fluorinated thiosemicarbazone derivative- 2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway.

Zhao Y, Guo C, Wang L, Wang S, Li X, Jiang B, Wu N, Guo S, Zhang R, Liu K, Shi D. Zhao Y, et al. Among authors: wang l, wang s. Biochem Biophys Res Commun. 2017 Sep 9;491(1):65-71. doi: 10.1016/j.bbrc.2017.07.042. Epub 2017 Jul 8. Biochem Biophys Res Commun. 2017. PMID: 28698138

9

Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment.

Wang L, Guo C, Li X, Yu X, Li X, Xu K, Jiang B, Jia X, Li C, Shi D. Wang L, et al. Eur J Med Chem. 2019 Sep 1;177:153-170. doi: 10.1016/j.ejmech.2019.05.044. Epub 2019 May 20. Eur J Med Chem. 2019. PMID: 31132531

10

A novel dibenzo[a,c]phenazine-based fluorescent probe for fast and selective detection of thiophenols in environmental water.

Guo S, Wang L, Jiang B. Guo S, et al. Among authors: wang l. RSC Adv. 2022 Mar 18;12(14):8611-8616. doi: 10.1039/d1ra08605g. eCollection 2022 Mar 15. RSC Adv. 2022. PMID: 35424794 Free PMC article.

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