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Subchronic N-acetylcysteine Treatment Decreases Brain Kynurenic Acid Levels and Improves Cognitive Performance in Mice.
Blanco Ayala TB, Ramírez Ortega DR, Ovalle Rodríguez PO, Pineda B, Pérez de la Cruz GP, González Esquivel DG, Schwarcz R, Sathyasaikumar KV, Jiménez Anguiano AJ, Pérez de la Cruz VP. Blanco Ayala TB, et al. Among authors: sathyasaikumar kv. Antioxidants (Basel). 2021 Jan 20;10(2):147. doi: 10.3390/antiox10020147. Antioxidants (Basel). 2021. PMID: 33498402 Free PMC article.
Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites.
Breda C, Sathyasaikumar KV, Sograte Idrissi S, Notarangelo FM, Estranero JG, Moore GG, Green EW, Kyriacou CP, Schwarcz R, Giorgini F. Breda C, et al. Among authors: sathyasaikumar kv. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5435-40. doi: 10.1073/pnas.1604453113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114543 Free PMC article.
Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice.
Larkin PB, Sathyasaikumar KV, Notarangelo FM, Funakoshi H, Nakamura T, Schwarcz R, Muchowski PJ. Larkin PB, et al. Among authors: sathyasaikumar kv. Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2345-2354. doi: 10.1016/j.bbagen.2016.07.002. Epub 2016 Jul 5. Biochim Biophys Acta. 2016. PMID: 27392942 Free PMC article.
29 results