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Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1.
Renders S, Svendsen AF, Panten J, Rama N, Maryanovich M, Sommerkamp P, Ladel L, Redavid AR, Gibert B, Lazare S, Ducarouge B, Schönberger K, Narr A, Tourbez M, Dethmers-Ausema B, Zwart E, Hotz-Wagenblatt A, Zhang D, Korn C, Zeisberger P, Przybylla A, Sohn M, Mendez-Ferrer S, Heikenwälder M, Brune M, Klimmeck D, Bystrykh L, Frenette PS, Mehlen P, de Haan G, Cabezas-Wallscheid N, Trumpp A. Renders S, et al. Among authors: trumpp a. Nat Commun. 2021 Jan 27;12(1):608. doi: 10.1038/s41467-020-20801-0. Nat Commun. 2021. PMID: 33504783 Free PMC article.
Bone-marrow haematopoietic-stem-cell niches.
Wilson A, Trumpp A. Wilson A, et al. Among authors: trumpp a. Nat Rev Immunol. 2006 Feb;6(2):93-106. doi: 10.1038/nri1779. Nat Rev Immunol. 2006. PMID: 16491134 Review.
IFNalpha activates dormant haematopoietic stem cells in vivo.
Essers MA, Offner S, Blanco-Bose WE, Waibler Z, Kalinke U, Duchosal MA, Trumpp A. Essers MA, et al. Among authors: trumpp a. Nature. 2009 Apr 16;458(7240):904-8. doi: 10.1038/nature07815. Epub 2009 Feb 11. Nature. 2009. PMID: 19212321
Awakening dormant haematopoietic stem cells.
Trumpp A, Essers M, Wilson A. Trumpp A, et al. Nat Rev Immunol. 2010 Mar;10(3):201-9. doi: 10.1038/nri2726. Nat Rev Immunol. 2010. PMID: 20182459
Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model.
Cabezas-Wallscheid N, Eichwald V, de Graaf J, Löwer M, Lehr HA, Kreft A, Eshkind L, Hildebrandt A, Abassi Y, Heck R, Dehof AK, Ohngemach S, Sprengel R, Wörtge S, Schmitt S, Lotz J, Meyer C, Kindler T, Zhang DE, Kaina B, Castle JC, Trumpp A, Sahin U, Bockamp E. Cabezas-Wallscheid N, et al. Among authors: trumpp a. EMBO Mol Med. 2013 Dec;5(12):1804-20. doi: 10.1002/emmm.201302661. Epub 2013 Oct 4. EMBO Mol Med. 2013. PMID: 24124051 Free PMC article.
Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B.
Carnevalli LS, Scognamiglio R, Cabezas-Wallscheid N, Rahmig S, Laurenti E, Masuda K, Jöckel L, Kuck A, Sujer S, Polykratis A, Erlacher M, Pasparakis M, Essers MA, Trumpp A. Carnevalli LS, et al. Among authors: trumpp a. J Exp Med. 2014 May 5;211(5):769-79. doi: 10.1084/jem.20131072. Epub 2014 Apr 21. J Exp Med. 2014. PMID: 24752302 Free PMC article.
244 results