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Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers.
Wolpaw AJ, Bayliss R, Büchel G, Dang CV, Eilers M, Gustafson WC, Hansen GH, Jura N, Knapp S, Lemmon MA, Levens D, Maris JM, Marmorstein R, Metallo SJ, Park JR, Penn LZ, Rape M, Roussel MF, Shokat KM, Tansey WP, Verba KA, Vos SM, Weiss WA, Wolf E, Mossé YP. Wolpaw AJ, et al. Among authors: metallo sj. Cancer Res. 2021 Apr 1;81(7):1627-1632. doi: 10.1158/0008-5472.CAN-20-3108. Epub 2021 Jan 28. Cancer Res. 2021. PMID: 33509943 Free PMC article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 35553590
Improved low molecular weight Myc-Max inhibitors.
Wang H, Hammoudeh DI, Follis AV, Reese BE, Lazo JS, Metallo SJ, Prochownik EV. Wang H, et al. Among authors: metallo sj. Mol Cancer Ther. 2007 Sep;6(9):2399-408. doi: 10.1158/1535-7163.MCT-07-0005. Mol Cancer Ther. 2007. PMID: 17876039
Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1.
Barber-Rotenberg JS, Selvanathan SP, Kong Y, Erkizan HV, Snyder TM, Hong SP, Kobs CL, South NL, Summer S, Monroe PJ, Chruszcz M, Dobrev V, Tosso PN, Scher LJ, Minor W, Brown ML, Metallo SJ, Üren A, Toretsky JA. Barber-Rotenberg JS, et al. Among authors: metallo sj. Oncotarget. 2012 Feb;3(2):172-82. doi: 10.18632/oncotarget.454. Oncotarget. 2012. PMID: 22383402 Free PMC article.
27 results