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Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers.
Wolpaw AJ, Bayliss R, Büchel G, Dang CV, Eilers M, Gustafson WC, Hansen GH, Jura N, Knapp S, Lemmon MA, Levens D, Maris JM, Marmorstein R, Metallo SJ, Park JR, Penn LZ, Rape M, Roussel MF, Shokat KM, Tansey WP, Verba KA, Vos SM, Weiss WA, Wolf E, Mossé YP. Wolpaw AJ, et al. Among authors: wolf e. Cancer Res. 2021 Apr 1;81(7):1627-1632. doi: 10.1158/0008-5472.CAN-20-3108. Epub 2021 Jan 28. Cancer Res. 2021. PMID: 33509943 Free PMC article. Review.
Miz1 is required to maintain autophagic flux.
Wolf E, Gebhardt A, Kawauchi D, Walz S, von Eyss B, Wagner N, Renninger C, Krohne G, Asan E, Roussel MF, Eilers M. Wolf E, et al. Nat Commun. 2013;4:2535. doi: 10.1038/ncomms3535. Nat Commun. 2013. PMID: 24088869 Free PMC article.
The role of MIZ-1 in MYC-dependent tumorigenesis.
Wiese KE, Walz S, von Eyss B, Wolf E, Athineos D, Sansom O, Eilers M. Wiese KE, et al. Among authors: wolf e. Cold Spring Harb Perspect Med. 2013 Dec 1;3(12):a014290. doi: 10.1101/cshperspect.a014290. Cold Spring Harb Perspect Med. 2013. PMID: 24296348 Free PMC article. Review.
Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.
Baumgart S, Chen NM, Siveke JT, König A, Zhang JS, Singh SK, Wolf E, Bartkuhn M, Esposito I, Heßmann E, Reinecke J, Nikorowitsch J, Brunner M, Singh G, Fernandez-Zapico ME, Smyrk T, Bamlet WR, Eilers M, Neesse A, Gress TM, Billadeau DD, Tuveson D, Urrutia R, Ellenrieder V. Baumgart S, et al. Among authors: wolf e. Cancer Discov. 2014 Jun;4(6):688-701. doi: 10.1158/2159-8290.CD-13-0593. Epub 2014 Apr 2. Cancer Discov. 2014. PMID: 24694735 Free PMC article.
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
Walz S, Lorenzin F, Morton J, Wiese KE, von Eyss B, Herold S, Rycak L, Dumay-Odelot H, Karim S, Bartkuhn M, Roels F, Wüstefeld T, Fischer M, Teichmann M, Zender L, Wei CL, Sansom O, Wolf E, Eilers M. Walz S, et al. Among authors: wolf e. Nature. 2014 Jul 24;511(7510):483-7. doi: 10.1038/nature13473. Epub 2014 Jul 9. Nature. 2014. PMID: 25043018 Free PMC article.
Taming of the beast: shaping Myc-dependent amplification.
Wolf E, Lin CY, Eilers M, Levens DL. Wolf E, et al. Trends Cell Biol. 2015 Apr;25(4):241-8. doi: 10.1016/j.tcb.2014.10.006. Epub 2014 Dec 1. Trends Cell Biol. 2015. PMID: 25475704 Free PMC article. Review.
2,456 results