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Chloroquine for treatment of COVID-19 results in subtherapeutic exposure and prolonged QTc intervals.
Brüggemann RJ, Moes DJAR, van Rhee KP, van 't Veer NE, Koch BCP, van Rossum M, Windsant-van den Tweel AV, Reijers MHE, van Kimmenade RRJ, Rahamat-Langedoen JC, Rettig TCD, van Raalte R, van Paassen J, Polderman FN, van der Linden PD, Frenzel T, de Mast Q, Burger DM, Schouten J, van de Veerdonk FL, Pickkers P, Ter Heine R. Brüggemann RJ, et al. Among authors: windsant van den tweel av. Int J Antimicrob Agents. 2021 Mar;57(3):106293. doi: 10.1016/j.ijantimicag.2021.106293. Epub 2021 Jan 27. Int J Antimicrob Agents. 2021. PMID: 33515687 Free PMC article. No abstract available.