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Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging.
Ziegler DV, Vindrieux D, Goehrig D, Jaber S, Collin G, Griveau A, Wiel C, Bendridi N, Djebali S, Farfariello V, Prevarskaya N, Payen L, Marvel J, Aubert S, Flaman JM, Rieusset J, Martin N, Bernard D. Ziegler DV, et al. Among authors: goehrig d. Nat Commun. 2021 Feb 1;12(1):720. doi: 10.1038/s41467-021-20993-z. Nat Commun. 2021. PMID: 33526781 Free PMC article.
Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A.
Zhao Y, Wu Z, Chanal M, Guillaumond F, Goehrig D, Bachy S, Principe M, Ziverec A, Flaman JM, Collin G, Tomasini R, Pasternack A, Ritvos O, Vasseur S, Bernard D, Hennino A, Bertolino P. Zhao Y, et al. Among authors: goehrig d. Cancer Res. 2020 Aug 15;80(16):3359-3371. doi: 10.1158/0008-5472.CAN-19-3763. Epub 2020 Jun 17. Cancer Res. 2020. PMID: 32554750
Phospholipase A2 receptor 1 promotes lung cell senescence and emphysema in obstructive lung disease.
Beaulieu D, Attwe A, Breau M, Lipskaia L, Marcos E, Born E, Huang J, Abid S, Derumeaux G, Houssaini A, Maitre B, Lefevre M, Vienney N, Bertolino P, Jaber S, Noureddine H, Goehrig D, Vindrieux D, Bernard D, Adnot S. Beaulieu D, et al. Among authors: goehrig d. Eur Respir J. 2021 Aug 12;58(2):2000752. doi: 10.1183/13993003.00752-2020. Print 2021 Aug. Eur Respir J. 2021. PMID: 33509955 Free article.
PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging.
Huna A, Griveau A, Vindrieux D, Jaber S, Flaman JM, Goehrig D, Azzi L, Médard JJ, Djebali S, Hernandez-Vargas H, Dante R, Payen L, Marvel J, Bertolino P, Aubert S, Dubus P, Bernard D. Huna A, et al. Among authors: goehrig d. Cell Death Dis. 2021 Feb 16;12(2):190. doi: 10.1038/s41419-021-03468-3. Cell Death Dis. 2021. PMID: 33594040 Free PMC article.
NF-κB-dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells.
Raynard C, Ma X, Huna A, Tessier N, Massemin A, Zhu K, Flaman JM, Moulin F, Goehrig D, Medard JJ, Vindrieux D, Treilleux I, Hernandez-Vargas H, Ducreux S, Martin N, Bernard D. Raynard C, et al. Among authors: goehrig d. Aging Cell. 2022 Jul;21(7):e13632. doi: 10.1111/acel.13632. Epub 2022 Jun 2. Aging Cell. 2022. PMID: 35653631 Free PMC article.
A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression.
Czarnecka-Herok J, Zhu K, Flaman JM, Goehrig D, Vernier M, Makulyte G, Lamboux A, Dragic H, Rhinn M, Médard JJ, Faury G, Bertolino P, Balter V, Debret R, Adnot S, Martin N, Bernard D. Czarnecka-Herok J, et al. Among authors: goehrig d. Redox Biol. 2024 Jul;73:103204. doi: 10.1016/j.redox.2024.103204. Epub 2024 May 22. Redox Biol. 2024. PMID: 38810421 Free PMC article.
20 results