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Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity.
Surette FA, Guthmiller JJ, Li L, Sturtz AJ, Vijay R, Pope RL, McClellan BL, Pack AD, Zander RA, Shao P, Lan LY, Fernandez-Ruiz D, Heath WR, Wilson PC, Butler NS. Surette FA, et al. Among authors: lan ly. PLoS Pathog. 2021 Feb 2;17(2):e1009288. doi: 10.1371/journal.ppat.1009288. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33529242 Free PMC article.
Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses.
Guthmiller JJ, Lan LY, Fernández-Quintero ML, Han J, Utset HA, Bitar DJ, Hamel NJ, Stovicek O, Li L, Tepora M, Henry C, Neu KE, Dugan HL, Borowska MT, Chen YQ, Liu STH, Stamper CT, Zheng NY, Huang M, Palm AE, García-Sastre A, Nachbagauer R, Palese P, Coughlan L, Krammer F, Ward AB, Liedl KR, Wilson PC. Guthmiller JJ, et al. Among authors: lan ly. Immunity. 2020 Dec 15;53(6):1230-1244.e5. doi: 10.1016/j.immuni.2020.10.005. Epub 2020 Oct 22. Immunity. 2020. PMID: 33096040 Free PMC article.
Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans.
Dugan HL, Guthmiller JJ, Arevalo P, Huang M, Chen YQ, Neu KE, Henry C, Zheng NY, Lan LY, Tepora ME, Stovicek O, Bitar D, Palm AE, Stamper CT, Changrob S, Utset HA, Coughlan L, Krammer F, Cobey S, Wilson PC. Dugan HL, et al. Among authors: lan ly. Sci Transl Med. 2020 Dec 9;12(573):eabd3601. doi: 10.1126/scitranslmed.abd3601. Sci Transl Med. 2020. PMID: 33298562 Free PMC article.
Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Guthmiller JJ, Han J, Utset HA, Li L, Lan LY, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, de la Peña AT, Rosado V, Dugan HL, Zheng NY, Tepora ME, Bitar DJ, Changrob S, Strohmeier S, Huang M, García-Sastre A, Liedl KR, Bloom JD, Nachbagauer R, Palese P, Krammer F, Coughlan L, Ward AB, Wilson PC. Guthmiller JJ, et al. Among authors: lan ly. Nature. 2022 Feb;602(7896):314-320. doi: 10.1038/s41586-021-04356-8. Epub 2021 Dec 23. Nature. 2022. PMID: 34942633 Free PMC article.
Improved integration of single-cell transcriptome and surface protein expression by LinQ-View.
Li L, Dugan HL, Stamper CT, Lan LY, Asby NW, Knight M, Stovicek O, Zheng NY, Madariaga ML, Shanmugarajah K, Jansen MO, Changrob S, Utset HA, Henry C, Nelson C, Jedrzejczak RP, Fremont DH, Joachimiak A, Krammer F, Huang J, Khan AA, Wilson PC. Li L, et al. Among authors: lan ly. Cell Rep Methods. 2021 Jul 23;1(4):100056. doi: 10.1016/j.crmeth.2021.100056. eCollection 2021 Aug 23. Cell Rep Methods. 2021. PMID: 35475142 Free PMC article.
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