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Pressurized Intraperitoneal Aerosol Chemotherapy (Oxaliplatin) for Unresectable Colorectal Peritoneal Metastases: A Multicenter, Single-Arm, Phase II Trial (CRC-PIPAC).
Rovers KP, Wassenaar ECE, Lurvink RJ, Creemers GM, Burger JWA, Los M, Huysentruyt CJR, van Lijnschoten G, Nederend J, Lahaye MJ, Deenen MJ, Wiezer MJ, Nienhuijs SW, Boerma D, de Hingh IHJT. Rovers KP, et al. Among authors: deenen mj. Ann Surg Oncol. 2021 Sep;28(9):5311-5326. doi: 10.1245/s10434-020-09558-4. Epub 2021 Feb 5. Ann Surg Oncol. 2021. PMID: 33544279 Clinical Trial.
Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC).
Rovers KP, Lurvink RJ, Wassenaar EC, Kootstra TJ, Scholten HJ, Tajzai R, Deenen MJ, Nederend J, Lahaye MJ, Huysentruyt CJ, van 't Erve I, Fijneman RJ, Constantinides A, Kranenburg O, Los M, Thijs AM, Creemers GM, Burger JW, Wiezer MJ, Boerma D, Nienhuijs SW, de Hingh IH. Rovers KP, et al. Among authors: deenen mj. BMJ Open. 2019 Jul 27;9(7):e030408. doi: 10.1136/bmjopen-2019-030408. BMJ Open. 2019. PMID: 31352425 Free PMC article.
Concomitant intraperitoneal and systemic chemotherapy for extensive peritoneal metastases of colorectal origin: protocol of the multicentre, open-label, phase I, dose-escalation INTERACT trial.
de Boer NL, Brandt-Kerkhof ARM, Madsen EVE, Diepeveen M, van Meerten E, van Eerden RAG, de Man FM, Bouamar R, Koolen SLW, de Hingh IHJT, Bakkers C, Rovers KP, Creemers GM, Deenen MJ, Kranenburg OW, Constantinides A, Mathijssen RHJ, Verhoef C, Burger JWA; Dutch Peritoneal Oncology Group (DPOG); Dutch Colorectal Cancer Group (DCCG). de Boer NL, et al. Among authors: deenen mj. BMJ Open. 2019 Dec 8;9(12):e034508. doi: 10.1136/bmjopen-2019-034508. BMJ Open. 2019. PMID: 31818845 Free PMC article.
Identification of pharmacogenetic biomarkers for efficacy of cytoreductive surgery plus hyperthermic intraperitoneal mitomycin C in patients with colorectal peritoneal metastases.
Hulshof EC, Lurvink RJ, Caserta N, de Hingh IHJT, van Wezel T, Böhringer S, Swen JJ, Gelderblom H, Guchelaar HJ, Deenen MJ. Hulshof EC, et al. Among authors: deenen mj. Eur J Surg Oncol. 2020 Oct;46(10 Pt A):1925-1931. doi: 10.1016/j.ejso.2020.04.019. Epub 2020 Apr 15. Eur J Surg Oncol. 2020. PMID: 32354538
Systemic Pharmacokinetics of Oxaliplatin After Intraperitoneal Administration by Electrostatic Pressurized Intraperitoneal Aerosol Chemotherapy (ePIPAC) in Patients with Unresectable Colorectal Peritoneal Metastases in the CRC-PIPAC Trial.
Lurvink RJ, Tajzai R, Rovers KP, Wassenaar ECE, Moes DAR, Pluimakers G, Boerma D, Burger JWA, Nienhuijs SW, de Hingh IHJT, Deenen MJ. Lurvink RJ, et al. Among authors: deenen mj. Ann Surg Oncol. 2021 Jan;28(1):265-272. doi: 10.1245/s10434-020-08743-9. Epub 2020 Jun 22. Ann Surg Oncol. 2021. PMID: 32572849
Genetic Variants in DNA Repair Pathways as Potential Biomarkers in Predicting Treatment Outcome of Intraperitoneal Chemotherapy in Patients With Colorectal Peritoneal Metastasis: A Systematic Review.
Hulshof EC, Lim L, de Hingh IHJT, Gelderblom H, Guchelaar HJ, Deenen MJ. Hulshof EC, et al. Among authors: deenen mj. Front Pharmacol. 2020 Oct 6;11:577968. doi: 10.3389/fphar.2020.577968. eCollection 2020. Front Pharmacol. 2020. PMID: 33117169 Free PMC article.
RE: Phase I dose escalation study of oxaliplatin delivered via a laparoscopic approach using pressurized intraperitoneal aerosol chemotherapy (PIPAC) for advanced peritoneal metastases of gastrointestinal tract cancers: PIPAC-oxaliplatin for peritoneal metastases of gastrointestinal cancers.
Rovers KP, Lurvink RJ, Deenen MJ, de Hingh IHJT. Rovers KP, et al. Among authors: deenen mj. Eur J Cancer. 2021 Apr;147:182-184. doi: 10.1016/j.ejca.2021.01.002. Epub 2021 Feb 24. Eur J Cancer. 2021. PMID: 33640212 No abstract available.
First-line palliative systemic therapy alternated with electrostatic pressurised intraperitoneal aerosol chemotherapy (oxaliplatin) for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, single-arm, phase II study (CRC-PIPAC-II).
Lurvink RJ, Rauwerdink P, Rovers KP, Wassenaar ECE, Deenen MJ, Nederend J, Huysentruyt CJR, van 't Erve I, Fijneman RJA, van der Hoeven EJRJ, Seldenrijk CA, Constantinides A, Kranenburg O, Los M, Herbschleb KH, Thijs AMJ, Creemers GM, Burger JWA, Wiezer MJ, Nienhuijs SW, Boerma D, de Hingh IHJT. Lurvink RJ, et al. Among authors: deenen mj. BMJ Open. 2021 Mar 30;11(3):e044811. doi: 10.1136/bmjopen-2020-044811. BMJ Open. 2021. PMID: 33785492 Free PMC article.
First-line palliative systemic therapy alternated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for unresectable colorectal peritoneal metastases: A single-arm phase II trial (CRC-PIPAC-II).
Rauwerdink P, van de Vlasakker VCJ, Wassenaar ECE, Rovers KP, Los M, Herbschleb KH, Creemers GM, Thijs AMJ, Raicu MG, Huysentruyt CJR, van der Hoeven EJRJ, Nederend J, Peeters RYM, Deenen MJ, Elias SG, Fijneman RJA, Constantinides A, Kranenburg O, Burger PWA, Nienhuijs SW, Wiezer RJ, Lurvink RJ, de Hingh IHJT, Boerma D. Rauwerdink P, et al. Among authors: deenen mj. Eur J Surg Oncol. 2024 Sep;50(9):108487. doi: 10.1016/j.ejso.2024.108487. Epub 2024 Jun 13. Eur J Surg Oncol. 2024. PMID: 38905732 Clinical Trial.
70 results