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Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors.
Shi Y, Yuan J, Rraklli V, Maxymovitz E, Cipullo M, Liu M, Li S, Westerlund I, Bedoya-Reina OC, Bullova P, Rorbach J, Juhlin CC, Stenman A, Larsson C, Kogner P, O'Sullivan MJ, Schlisio S, Holmberg J. Shi Y, et al. Among authors: rorbach j. Nucleic Acids Res. 2021 Mar 18;49(5):2509-2521. doi: 10.1093/nar/gkab054. Nucleic Acids Res. 2021. PMID: 33555349 Free PMC article.
C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis.
Gopalakrishna S, Pearce SF, Dinan AM, Schober FA, Cipullo M, Spåhr H, Khawaja A, Maffezzini C, Freyer C, Wredenberg A, Atanassov I, Firth AE, Rorbach J. Gopalakrishna S, et al. Among authors: rorbach j. Nucleic Acids Res. 2019 Sep 26;47(17):9386-9399. doi: 10.1093/nar/gkz684. Nucleic Acids Res. 2019. PMID: 31396629 Free PMC article.
MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition.
Busch JD, Cipullo M, Atanassov I, Bratic A, Silva Ramos E, Schöndorf T, Li X, Pearce SF, Milenkovic D, Rorbach J, Larsson NG. Busch JD, et al. Among authors: rorbach j. Cell Rep. 2019 Nov 5;29(6):1728-1738.e9. doi: 10.1016/j.celrep.2019.09.080. Cell Rep. 2019. PMID: 31693908 Free PMC article.
Methylation of Ribosomal RNA: A Mitochondrial Perspective.
Lopez Sanchez MIG, Cipullo M, Gopalakrishna S, Khawaja A, Rorbach J. Lopez Sanchez MIG, et al. Among authors: rorbach j. Front Genet. 2020 Jul 17;11:761. doi: 10.3389/fgene.2020.00761. eCollection 2020. Front Genet. 2020. PMID: 32765591 Free PMC article. Review.
Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly.
Cipullo M, Pearce SF, Lopez Sanchez IG, Gopalakrishna S, Krüger A, Schober F, Busch JD, Li X, Wredenberg A, Atanassov I, Rorbach J. Cipullo M, et al. Among authors: rorbach j. Nucleic Acids Res. 2021 Jan 11;49(1):354-370. doi: 10.1093/nar/gkaa1131. Nucleic Acids Res. 2021. PMID: 33283228 Free PMC article.
Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I, Sergiev P, Rorbach J, Amunts A. Itoh Y, et al. Among authors: rorbach j. Nature. 2022 Jun;606(7914):603-608. doi: 10.1038/s41586-022-04795-x. Epub 2022 Jun 8. Nature. 2022. PMID: 35676484 Free PMC article.
GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Cipullo M, Valentín Gesé G, Gopalakrishna S, Krueger A, Lobo V, Pirozhkova MA, Marks J, Páleníková P, Shiriaev D, Liu Y, Misic J, Cai Y, Nguyen MD, Abdelbagi A, Li X, Minczuk M, Hafner M, Benhalevy D, Sarshad AA, Atanassov I, Hällberg BM, Rorbach J. Cipullo M, et al. Among authors: rorbach j. Nat Commun. 2024 Jul 5;15(1):5664. doi: 10.1038/s41467-024-50011-x. Nat Commun. 2024. PMID: 38969660 Free PMC article.
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