Shi Y - Search Results

1

Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors.

Shi Y, Yuan J, Rraklli V, Maxymovitz E, Cipullo M, Liu M, Li S, Westerlund I, Bedoya-Reina OC, Bullova P, Rorbach J, Juhlin CC, Stenman A, Larsson C, Kogner P, O'Sullivan MJ, Schlisio S, Holmberg J. Shi Y, et al. Nucleic Acids Res. 2021 Mar 18;49(5):2509-2521. doi: 10.1093/nar/gkab054. Nucleic Acids Res. 2021. PMID: 33555349 Free PMC article.

2

Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.

Westerlund I, Shi Y, Toskas K, Fell SM, Li S, Surova O, Södersten E, Kogner P, Nyman U, Schlisio S, Holmberg J. Westerlund I, et al. Among authors: shi y. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6137-E6146. doi: 10.1073/pnas.1700655114. Epub 2017 Jul 10. Proc Natl Acad Sci U S A. 2017. PMID: 28696319 Free PMC article.

3

Reply to Mohlin et al.: High levels of EPAS1 are closely associated with key features of low-risk neuroblastoma.

Westerlund I, Shi Y, Toskas K, Fell SM, Li S, Södersten E, Schlisio S, Holmberg J. Westerlund I, et al. Among authors: shi y. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10859-E10860. doi: 10.1073/pnas.1718429115. Epub 2017 Dec 12. Proc Natl Acad Sci U S A. 2017. PMID: 29233947 Free PMC article. No abstract available.

4

EPAS1/HIF2α correlates with features of low-risk neuroblastoma and with adrenal chromaffin cell differentiation during sympathoadrenal development.

Westerlund I, Shi Y, Holmberg J. Westerlund I, et al. Among authors: shi y. Biochem Biophys Res Commun. 2019 Jan 22;508(4):1233-1239. doi: 10.1016/j.bbrc.2018.12.076. Epub 2018 Dec 15. Biochem Biophys Res Commun. 2019. PMID: 30563765

5

Dual targeting of wild-type and mutant p53 by small molecule RITA results in the inhibition of N-Myc and key survival oncogenes and kills neuroblastoma cells in vivo and in vitro.

Burmakin M, Shi Y, Hedström E, Kogner P, Selivanova G. Burmakin M, et al. Among authors: shi y. Clin Cancer Res. 2013 Sep 15;19(18):5092-103. doi: 10.1158/1078-0432.CCR-12-2211. Epub 2013 Jul 17. Clin Cancer Res. 2013. PMID: 23864164

6

Editor's Note: Dual Targeting of Wild-Type and Mutant p53 by Small-molecule RITA Results in the Inhibition of N-Myc and Key Survival Oncogenes and Kills Neuroblastoma Cells In Vivo and In Vitro.

Burmakin M, Shi Y, Hedström E, Kogner P, Selivanova G. Burmakin M, et al. Among authors: shi y. Clin Cancer Res. 2021 Sep 1;27(17):4943. doi: 10.1158/1078-0432.CCR-21-2435. Clin Cancer Res. 2021. PMID: 34470814 No abstract available.

7

Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds.

Peuget S, Zhu J, Sanz G, Singh M, Gaetani M, Chen X, Shi Y, Saei AA, Visnes T, Lindström MS, Rihani A, Moyano-Galceran L, Carlson JW, Hjerpe E, Joneborg U, Lehti K, Hartman J, Helleday T, Zubarev R, Selivanova G. Peuget S, et al. Among authors: shi y. Cancer Res. 2020 Apr 1;80(7):1538-1550. doi: 10.1158/0008-5472.CAN-19-2069. Epub 2020 Feb 4. Cancer Res. 2020. PMID: 32019870

8

ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis.

Shi Y, Nikulenkov F, Zawacka-Pankau J, Li H, Gabdoulline R, Xu J, Eriksson S, Hedström E, Issaeva N, Kel A, Arnér ES, Selivanova G. Shi Y, et al. Cell Death Differ. 2014 Apr;21(4):612-23. doi: 10.1038/cdd.2013.186. Epub 2014 Jan 10. Cell Death Differ. 2014. PMID: 24413150 Free PMC article.

9

JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress.

Kostecka A, Sznarkowska A, Meller K, Acedo P, Shi Y, Mohammad Sakil HA, Kawiak A, Lion M, Królicka A, Wilhelm M, Inga A, Zawacka-Pankau J. Kostecka A, et al. Among authors: shi y. Cell Death Dis. 2014 Oct 23;5(10):e1484. doi: 10.1038/cddis.2014.408. Cell Death Dis. 2014. PMID: 25341038 Free PMC article.

10

Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis.

Grinkevich VV, Nikulenkov F, Shi Y, Enge M, Bao W, Maljukova A, Gluch A, Kel A, Sangfelt O, Selivanova G. Grinkevich VV, et al. Among authors: shi y. Cancer Cell. 2009 May 5;15(5):441-53. doi: 10.1016/j.ccr.2009.03.021. Cancer Cell. 2009. PMID: 19411072 Free article.

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