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Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease.
Schmid B, Holst B, Clausen C, Bahnassawy L, Reinhardt P, Bakker MHM, Díaz-Guerra E, Vicario C, Martino-Adami PV, Thoenes M, Ramirez A, Fliessbach K, Grezella C, Brüstle O, Peitz M, Ebneth A, Cabrera-Socorro A. Schmid B, et al. Among authors: grezella c. Stem Cell Res. 2021 Apr;52:102180. doi: 10.1016/j.scr.2021.102180. Epub 2021 Feb 2. Stem Cell Res. 2021. PMID: 33556820 Free article.
Effects of senolytic drugs on human mesenchymal stromal cells.
Grezella C, Fernandez-Rebollo E, Franzen J, Ventura Ferreira MS, Beier F, Wagner W. Grezella C, et al. Stem Cell Res Ther. 2018 Apr 18;9(1):108. doi: 10.1186/s13287-018-0857-6. Stem Cell Res Ther. 2018. PMID: 29669575 Free PMC article.
DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift.
Franzen J, Georgomanolis T, Selich A, Kuo CC, Stöger R, Brant L, Mulabdić MS, Fernandez-Rebollo E, Grezella C, Ostrowska A, Begemann M, Nikolić M, Rath B, Ho AD, Rothe M, Schambach A, Papantonis A, Wagner W. Franzen J, et al. Among authors: grezella c. Commun Biol. 2021 May 19;4(1):598. doi: 10.1038/s42003-021-02116-y. Commun Biol. 2021. PMID: 34011964 Free PMC article.