Tyner JW - Search Results

1

Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax.

Moses BS, McCullough S, Fox JM, Mott BT, Bentzen SM, Kim M, Tyner JW, Lapidus RG, Emadi A, Rudek MA, Kingsbury TJ, Civin CI. Moses BS, et al. Among authors: tyner jw. Blood Adv. 2021 Feb 9;5(3):711-724. doi: 10.1182/bloodadvances.2020003429. Blood Adv. 2021. PMID: 33560385 Free PMC article.

2

CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms.

Tyner JW, Bumm TG, Deininger J, Wood L, Aichberger KJ, Loriaux MM, Druker BJ, Burns CJ, Fantino E, Deininger MW. Tyner JW, et al. Blood. 2010 Jun 24;115(25):5232-40. doi: 10.1182/blood-2009-05-223727. Epub 2010 Apr 12. Blood. 2010. PMID: 20385788 Free PMC article.

3

Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations.

Traer E, Javidi-Sharifi N, Agarwal A, Dunlap J, English I, Martinez J, Tyner JW, Wong M, Druker BJ. Traer E, et al. Among authors: tyner jw. Blood. 2014 Mar 6;123(10):1516-24. doi: 10.1182/blood-2013-07-518381. Epub 2014 Jan 9. Blood. 2014. PMID: 24408322 Free PMC article.

4

Integrated analysis of CRLF2 signaling in acute lymphoblastic leukemia identifies Polo-like kinase 1 as a potential therapeutic target.

Huang TC, Cutler J, Bharne S, Zhong J, Weinstock D, Tyner J, Gojo I, Civin C, Pandey A. Huang TC, et al. Leuk Lymphoma. 2015 May;56(5):1524-7. doi: 10.3109/10428194.2014.963076. Epub 2014 Nov 5. Leuk Lymphoma. 2015. PMID: 25213184 Free PMC article. No abstract available.

5

Stability of patient-specific features of altered DNA replication timing in xenografts of primary human acute lymphoblastic leukemia.

Sasaki T, Rivera-Mulia JC, Vera D, Zimmerman J, Das S, Padget M, Nakamichi N, Chang BH, Tyner J, Druker BJ, Weng AP, Civin CI, Eaves CJ, Gilbert DM. Sasaki T, et al. Exp Hematol. 2017 Jul;51:71-82.e3. doi: 10.1016/j.exphem.2017.04.004. Epub 2017 Apr 19. Exp Hematol. 2017. PMID: 28433605 Free PMC article.

6

EPHB4 is a therapeutic target in AML and promotes leukemia cell survival via AKT.

Merchant AA, Jorapur A, McManus A, Liu R, Krasnoperov V, Chaudhry P, Singh M, Harton L, Agajanian M, Kim M, Triche TJ Jr, Druker BJ, Tyner JW, Gill PS. Merchant AA, et al. Among authors: tyner jw. Blood Adv. 2017 Aug 28;1(20):1635-1644. doi: 10.1182/bloodadvances.2017005694. eCollection 2017 Sep 12. Blood Adv. 2017. PMID: 29296810 Free PMC article.

7

CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells.

Edwards DK 5th, Watanabe-Smith K, Rofelty A, Damnernsawad A, Laderas T, Lamble A, Lind EF, Kaempf A, Mori M, Rosenberg M, d'Almeida A, Long N, Agarwal A, Sweeney DT, Loriaux M, McWeeney SK, Tyner JW. Edwards DK 5th, et al. Among authors: tyner jw. Blood. 2019 Feb 7;133(6):588-599. doi: 10.1182/blood-2018-03-838946. Epub 2018 Nov 13. Blood. 2019. PMID: 30425048 Free PMC article.

8

Simultaneous kinase inhibition with ibrutinib and BCL2 inhibition with venetoclax offers a therapeutic strategy for acute myeloid leukemia.

Eide CA, Kurtz SE, Kaempf A, Long N, Agarwal A, Tognon CE, Mori M, Druker BJ, Chang BH, Danilov AV, Tyner JW. Eide CA, et al. Among authors: tyner jw. Leukemia. 2020 Sep;34(9):2342-2353. doi: 10.1038/s41375-020-0764-6. Epub 2020 Feb 24. Leukemia. 2020. PMID: 32094466 Free PMC article.

9

Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.

Joshi SK, Qian K, Bisson WH, Watanabe-Smith K, Huang A, Bottomly D, Traer E, Tyner JW, McWeeney SK, Davare MA, Druker BJ, Tognon CE. Joshi SK, et al. Among authors: tyner jw. Blood. 2020 Jun 11;135(24):2159-2170. doi: 10.1182/blood.2019003691. Blood. 2020. PMID: 32315394 Free PMC article.

10

Concomitant use of a dual Src/ABL kinase inhibitor eliminates the in vitro efficacy of blinatumomab against Ph+ ALL.

Leonard JT, Kosaka Y, Malla P, LaTocha D, Lamble A, Hayes-Lattin B, Byrd K, Druker BJ, Tyner JW, Chang BH, Lind E. Leonard JT, et al. Among authors: tyner jw. Blood. 2021 Feb 18;137(7):939-944. doi: 10.1182/blood.2020005655. Blood. 2021. PMID: 32898857 Free PMC article.

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