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Page 1
MITOL promotes cell survival by degrading Parkin during mitophagy.
Shiiba I, Takeda K, Nagashima S, Ito N, Tokuyama T, Yamashita SI, Kanki T, Komatsu T, Urano Y, Fujikawa Y, Inatome R, Yanagi S. Shiiba I, et al. Among authors: tokuyama t. EMBO Rep. 2021 Mar 3;22(3):e49097. doi: 10.15252/embr.201949097. Epub 2021 Feb 10. EMBO Rep. 2021. PMID: 33565245 Free PMC article.
MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2.
Sugiura A, Nagashima S, Tokuyama T, Amo T, Matsuki Y, Ishido S, Kudo Y, McBride HM, Fukuda T, Matsushita N, Inatome R, Yanagi S. Sugiura A, et al. Among authors: tokuyama t. Mol Cell. 2013 Jul 11;51(1):20-34. doi: 10.1016/j.molcel.2013.04.023. Epub 2013 May 30. Mol Cell. 2013. PMID: 23727017 Free article.
Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis.
Maruyama T, Baba T, Maemoto Y, Hara-Miyauchi C, Hasegawa-Ogawa M, Okano HJ, Enda Y, Matsumoto K, Arimitsu N, Nakao K, Hamamoto H, Sekimizu K, Ohto-Nakanishi T, Nakanishi H, Tokuyama T, Yanagi S, Tagaya M, Tani K. Maruyama T, et al. Among authors: tokuyama t. Cell Death Dis. 2018 Jul 23;9(8):797. doi: 10.1038/s41419-018-0815-3. Cell Death Dis. 2018. PMID: 30038238 Free PMC article.
MITOL dysfunction causes dwarfism with anterior pituitary hypoplasia.
Matsuno K, Nagashima S, Shiiba I, Taniwaka K, Takeda K, Tokuyama T, Ito N, Matsushita N, Fukuda T, Ishido S, Inatome R, Yanagi S. Matsuno K, et al. Among authors: tokuyama t. J Biochem. 2020 Sep 1;168(3):305-312. doi: 10.1093/jb/mvaa050. J Biochem. 2020. PMID: 32302394
MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis.
Kitakata H, Endo J, Matsushima H, Yamamoto S, Ikura H, Hirai A, Koh S, Ichihara G, Hiraide T, Moriyama H, Shirakawa K, Goto S, Katsumata Y, Anzai A, Kataoka M, Tokuyama T, Ishido S, Yanagi S, Fukuda K, Sano M. Kitakata H, et al. Among authors: tokuyama t. J Mol Cell Cardiol. 2021 Dec;161:116-129. doi: 10.1016/j.yjmcc.2021.08.006. Epub 2021 Aug 12. J Mol Cell Cardiol. 2021. PMID: 34390730
281 results