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Page 1
Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides.
Tone Y, Mamchaoui K, Tsoumpra MK, Hashimoto Y, Terada R, Maruyama R, Gait MJ, Arzumanov AA, McClorey G, Imamura M, Takeda S, Yokota T, Wood MJA, Mouly V, Aoki Y. Tone Y, et al. Among authors: tsoumpra mk. Nucleic Acid Ther. 2021 Apr;31(2):172-181. doi: 10.1089/nat.2020.0907. Epub 2021 Feb 9. Nucleic Acid Ther. 2021. PMID: 33567244 Free PMC article.
How do we sense phosphate to regulate serum phosphate level?
Fukumoto S, Takashi Y, Tsoumpra MK, Sawatsubashi S, Matsumoto T. Fukumoto S, et al. Among authors: tsoumpra mk. J Bone Miner Metab. 2020 Jan;38(1):1-6. doi: 10.1007/s00774-019-01066-0. Epub 2019 Dec 3. J Bone Miner Metab. 2020. PMID: 31797064 Review.
Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation.
Takashi Y, Kosako H, Sawatsubashi S, Kinoshita Y, Ito N, Tsoumpra MK, Nangaku M, Abe M, Matsuhisa M, Kato S, Matsumoto T, Fukumoto S. Takashi Y, et al. Among authors: tsoumpra mk. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11418-11427. doi: 10.1073/pnas.1815166116. Epub 2019 May 16. Proc Natl Acad Sci U S A. 2019. PMID: 31097591 Free PMC article.
The relationship between the chemistry and biological activity of the bisphosphonates.
Ebetino FH, Hogan AM, Sun S, Tsoumpra MK, Duan X, Triffitt JT, Kwaasi AA, Dunford JE, Barnett BL, Oppermann U, Lundy MW, Boyde A, Kashemirov BA, McKenna CE, Russell RG. Ebetino FH, et al. Among authors: tsoumpra mk. Bone. 2011 Jul;49(1):20-33. doi: 10.1016/j.bone.2011.03.774. Epub 2011 Apr 9. Bone. 2011. PMID: 21497677 Review.
The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
Tsoumpra MK, Muniz JR, Barnett BL, Kwaasi AA, Pilka ES, Kavanagh KL, Evdokimov A, Walter RL, Von Delft F, Ebetino FH, Oppermann U, Russell RGG, Dunford JE. Tsoumpra MK, et al. Bone. 2015 Dec;81:478-486. doi: 10.1016/j.bone.2015.08.020. Epub 2015 Aug 28. Bone. 2015. PMID: 26318908 Free PMC article.
The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1-Fluoro-2-(Imidazo-[1,2-α]Pyridin-3-yl)-Ethyl-Bisphosphonate).
Lawson MA, Ebetino FH, Mazur A, Chantry AD, Paton-Hough J, Evans HR, Lath D, Tsoumpra MK, Lundy MW, Dobson RL, Quijano M, Kwaasi AA, Dunford JE, Duan X, Triffitt JT, Jeans G, Russell RGG. Lawson MA, et al. Among authors: tsoumpra mk. J Bone Miner Res. 2017 Sep;32(9):1860-1869. doi: 10.1002/jbmr.3138. Epub 2017 Apr 21. J Bone Miner Res. 2017. PMID: 28337806 Free PMC article.