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SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies.
Diamond M, Chen R, Xie X, Case J, Zhang X, VanBlargan L, Liu Y, Liu J, Errico J, Winkler E, Suryadevara N, Tahan S, Turner J, Kim W, Schmitz A, Thapa M, Wang D, Boon A, Pinto D, Presti R, O'Halloran J, Kim A, Deepak P, Fremont D, Corti D, Virgin H, Crowe J, Droit L, Ellebedy A, Shi PY, Gilchuk P. Diamond M, et al. Among authors: crowe j. Res Sq [Preprint]. 2021 Feb 10:rs.3.rs-228079. doi: 10.21203/rs.3.rs-228079/v1. Res Sq. 2021. Update in: Nat Med. 2021 Apr;27(4):717-726. doi: 10.1038/s41591-021-01294-w PMID: 33594356 Free PMC article. Updated. Preprint.
The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein.
Smith SA, de Alwis AR, Kose N, Harris E, Ibarra KD, Kahle KM, Pfaff JM, Xiang X, Doranz BJ, de Silva AM, Austin SK, Sukupolvi-Petty S, Diamond MS, Crowe JE Jr. Smith SA, et al. Among authors: crowe je jr. mBio. 2013 Nov 19;4(6):e00873-13. doi: 10.1128/mBio.00873-13. mBio. 2013. PMID: 24255124 Free PMC article.
Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Long F, Fong RH, Austin SK, Chen Z, Klose T, Fokine A, Liu Y, Porta J, Sapparapu G, Akahata W, Doranz BJ, Crowe JE Jr, Diamond MS, Rossmann MG. Long F, et al. Among authors: crowe je jr. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13898-903. doi: 10.1073/pnas.1515558112. Epub 2015 Oct 26. Proc Natl Acad Sci U S A. 2015. PMID: 26504196 Free PMC article.
Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.
Sapparapu G, Fernandez E, Kose N, Bin Cao, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE. Sapparapu G, et al. Among authors: crowe je. Nature. 2016 Dec 15;540(7633):443-447. doi: 10.1038/nature20564. Epub 2016 Nov 7. Nature. 2016. PMID: 27819683 Free PMC article.
Mxra8 is a receptor for multiple arthritogenic alphaviruses.
Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE Jr, Doranz BJ, Fremont DH, Diamond MS. Zhang R, et al. Among authors: crowe je jr. Nature. 2018 May;557(7706):570-574. doi: 10.1038/s41586-018-0121-3. Epub 2018 May 16. Nature. 2018. PMID: 29769725 Free PMC article.
1,247 results