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Page 1
Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.
Clark JC, Neagoe RAI, Zuidscherwoude M, Kavanagh DM, Slater A, Martin EM, Soave M, Stegner D, Nieswandt B, Poulter NS, Hummert J, Herten DP, Tomlinson MG, Hill SJ, Watson SP. Clark JC, et al. Among authors: poulter ns. Thromb Haemost. 2021 Nov;121(11):1435-1447. doi: 10.1055/a-1401-5014. Epub 2021 Apr 14. Thromb Haemost. 2021. PMID: 33638140
Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.
Pollitt AY, Poulter NS, Gitz E, Navarro-Nuñez L, Wang YJ, Hughes CE, Thomas SG, Nieswandt B, Douglas MR, Owen DM, Jackson DG, Dustin ML, Watson SP. Pollitt AY, et al. Among authors: poulter ns. J Biol Chem. 2014 Dec 26;289(52):35695-710. doi: 10.1074/jbc.M114.584284. Epub 2014 Nov 3. J Biol Chem. 2014. PMID: 25368330 Free PMC article.
Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation.
Haining EJ, Matthews AL, Noy PJ, Romanska HM, Harris HJ, Pike J, Morowski M, Gavin RL, Yang J, Milhiet PE, Berditchevski F, Nieswandt B, Poulter NS, Watson SP, Tomlinson MG. Haining EJ, et al. Among authors: poulter ns. Platelets. 2017 Nov;28(7):629-642. doi: 10.1080/09537104.2016.1254175. Epub 2016 Dec 29. Platelets. 2017. PMID: 28032533 Free PMC article.
Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI.
Montague SJ, Delierneux C, Lecut C, Layios N, Dinsdale RJ, Lee CS, Poulter NS, Andrews RK, Hampson P, Wearn CM, Maes N, Bishop J, Bamford A, Gardiner C, Lee WM, Iqbal T, Moiemen N, Watson SP, Oury C, Harrison P, Gardiner EE. Montague SJ, et al. Among authors: poulter ns. Blood Adv. 2018 Feb 13;2(3):240-251. doi: 10.1182/bloodadvances.2017011171. Blood Adv. 2018. PMID: 29437639 Free PMC article.
Comparison of the GPVI inhibitors losartan and honokiol.
Onselaer MB, Nagy M, Pallini C, Pike JA, Perrella G, Quintanilla LG, Eble JA, Poulter NS, Heemskerk JWM, Watson SP. Onselaer MB, et al. Among authors: poulter ns. Platelets. 2020;31(2):187-197. doi: 10.1080/09537104.2019.1585526. Epub 2019 Mar 8. Platelets. 2020. PMID: 30849265 Free PMC article.
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation.
Dunster JL, Unsworth AJ, Bye AP, Haining EJ, Sowa MA, Di Y, Sage T, Pallini C, Pike JA, Hardy AT, Nieswandt B, García Á, Watson SP, Poulter NS, Gibbins JM, Pollitt AY. Dunster JL, et al. Among authors: poulter ns. J Thromb Haemost. 2020 Feb;18(2):485-496. doi: 10.1111/jth.14673. Epub 2019 Dec 6. J Thromb Haemost. 2020. PMID: 31680418 Free PMC article.
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2.
Nicolson PLR, Nock SH, Hinds J, Garcia-Quintanilla L, Smith CW, Campos J, Brill A, Pike JA, Khan AO, Poulter NS, Kavanagh DM, Watson S, Watson CN, Clifford H, Huissoon AP, Pollitt AY, Eble JA, Pratt G, Watson SP, Hughes CE. Nicolson PLR, et al. Among authors: poulter ns. Haematologica. 2021 Jan 1;106(1):208-219. doi: 10.3324/haematol.2019.218545. Haematologica. 2021. PMID: 31949019 Free PMC article.
55 results