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Page 1
Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion.
Frangieh CJ, Melms JC, Thakore PI, Geiger-Schuller KR, Ho P, Luoma AM, Cleary B, Jerby-Arnon L, Malu S, Cuoco MS, Zhao M, Ager CR, Rogava M, Hovey L, Rotem A, Bernatchez C, Wucherpfennig KW, Johnson BE, Rozenblatt-Rosen O, Schadendorf D, Regev A, Izar B. Frangieh CJ, et al. Among authors: geiger schuller kr. Nat Genet. 2021 Mar;53(3):332-341. doi: 10.1038/s41588-021-00779-1. Epub 2021 Mar 1. Nat Genet. 2021. PMID: 33649592 Free PMC article.
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action.
McFarland JM, Paolella BR, Warren A, Geiger-Schuller K, Shibue T, Rothberg M, Kuksenko O, Colgan WN, Jones A, Chambers E, Dionne D, Bender S, Wolpin BM, Ghandi M, Tirosh I, Rozenblatt-Rosen O, Roth JA, Golub TR, Regev A, Aguirre AJ, Vazquez F, Tsherniak A. McFarland JM, et al. Nat Commun. 2020 Aug 27;11(1):4296. doi: 10.1038/s41467-020-17440-w. Nat Commun. 2020. PMID: 32855387 Free PMC article.
Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing.
Simmons SK, Lithwick-Yanai G, Adiconis X, Oberstrass F, Iremadze N, Geiger-Schuller K, Thakore PI, Frangieh CJ, Barad O, Almogy G, Rozenblatt-Rosen O, Regev A, Lipson D, Levin JZ. Simmons SK, et al. Nat Biotechnol. 2023 Feb;41(2):204-211. doi: 10.1038/s41587-022-01452-6. Epub 2022 Sep 15. Nat Biotechnol. 2023. PMID: 36109685 Free PMC article.
Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity.
Kumar P, Magala P, Geiger-Schuller KR, Majumdar A, Tolman JR, Wolberger C. Kumar P, et al. Among authors: geiger schuller kr. Nucleic Acids Res. 2015 Oct 15;43(18):9039-50. doi: 10.1093/nar/gkv845. Epub 2015 Aug 18. Nucleic Acids Res. 2015. PMID: 26286193 Free PMC article.
A transcription factor atlas of directed differentiation.
Joung J, Ma S, Tay T, Geiger-Schuller KR, Kirchgatterer PC, Verdine VK, Guo B, Arias-Garcia MA, Allen WE, Singh A, Kuksenko O, Abudayyeh OO, Gootenberg JS, Fu Z, Macrae RK, Buenrostro JD, Regev A, Zhang F. Joung J, et al. Among authors: geiger schuller kr. Cell. 2024 Jun 6;187(12):3161. doi: 10.1016/j.cell.2024.04.038. Epub 2024 May 2. Cell. 2024. PMID: 38697106 Free article. No abstract available.
A transcription factor atlas of directed differentiation.
Joung J, Ma S, Tay T, Geiger-Schuller KR, Kirchgatterer PC, Verdine VK, Guo B, Arias-Garcia MA, Allen WE, Singh A, Kuksenko O, Abudayyeh OO, Gootenberg JS, Fu Z, Macrae RK, Buenrostro JD, Regev A, Zhang F. Joung J, et al. Among authors: geiger schuller kr. Cell. 2023 Jan 5;186(1):209-229.e26. doi: 10.1016/j.cell.2022.11.026. Cell. 2023. PMID: 36608654 Free PMC article.