Janežič M - Search Results

1

A multidimensional computational exploration of congenital myasthenic syndrome causing mutations in human choline acetyltransferase.

Janežič M, Dileep KV, Zhang KYJ. Janežič M, et al. J Cell Biochem. 2021 Aug;122(8):787-800. doi: 10.1002/jcb.29913. Epub 2021 Mar 1. J Cell Biochem. 2021. PMID: 33650116

2

Crystal Structure and Structure-Based Discovery of Inhibitors of the Nematode Chitinase CeCht1.

Chen Q, Chen W, Kumar A, Jiang X, Janezic M, Zhang KYJ, Yang Q. Chen Q, et al. Among authors: janezic m. J Agric Food Chem. 2021 Mar 24;69(11):3519-3526. doi: 10.1021/acs.jafc.1c00162. Epub 2021 Mar 10. J Agric Food Chem. 2021. PMID: 33691404

3

Bioassays and In Silico Methods in the Identification of Human DNA Topoisomerase IIα Inhibitors.

Bergant K, Janezic M, Perdih A. Bergant K, et al. Among authors: janezic m. Curr Med Chem. 2018;25(28):3286-3318. doi: 10.2174/0929867325666180306165725. Curr Med Chem. 2018. PMID: 29508675 Review.

4

Substituted 4,5'-Bithiazoles as Catalytic Inhibitors of Human DNA Topoisomerase IIα.

Bergant Loboda K, Janežič M, Štampar M, Žegura B, Filipič M, Perdih A. Bergant Loboda K, et al. Among authors: janezic m. J Chem Inf Model. 2020 Jul 27;60(7):3662-3678. doi: 10.1021/acs.jcim.0c00202. Epub 2020 Jun 22. J Chem Inf Model. 2020. PMID: 32484690 Free PMC article.

5

Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα.

Bergant K, Janežič M, Valjavec K, Sosič I, Pajk S, Štampar M, Žegura B, Gobec S, Filipič M, Perdih A. Bergant K, et al. Among authors: janezic m. Eur J Med Chem. 2019 Aug 1;175:330-348. doi: 10.1016/j.ejmech.2019.04.055. Epub 2019 Apr 25. Eur J Med Chem. 2019. PMID: 31096154

6

Dynophore-Based Approach in Virtual Screening: A Case of Human DNA Topoisomerase IIα.

Janežič M, Valjavec K, Loboda KB, Herlah B, Ogris I, Kozorog M, Podobnik M, Grdadolnik SG, Wolber G, Perdih A. Janežič M, et al. Int J Mol Sci. 2021 Dec 15;22(24):13474. doi: 10.3390/ijms222413474. Int J Mol Sci. 2021. PMID: 34948269 Free PMC article.

7

4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIα targeting the ATP binding site.

Pogorelčnik B, Janežič M, Sosič I, Gobec S, Solmajer T, Perdih A. Pogorelčnik B, et al. Among authors: janezic m. Bioorg Med Chem. 2015 Aug 1;23(15):4218-4229. doi: 10.1016/j.bmc.2015.06.049. Epub 2015 Jul 2. Bioorg Med Chem. 2015. PMID: 26183545

8

Catalytic Mechanism of ATP Hydrolysis in the ATPase Domain of Human DNA Topoisomerase IIα.

Ogrizek M, Janežič M, Valjavec K, Perdih A. Ogrizek M, et al. Among authors: janezic m. J Chem Inf Model. 2022 Aug 22;62(16):3896-3909. doi: 10.1021/acs.jcim.2c00303. Epub 2022 Aug 10. J Chem Inf Model. 2022. PMID: 35948041 Free PMC article.

9

Nature-inspired substituted 3-(imidazol-2-yl) morpholines targeting human topoisomerase IIα: Dynophore-derived discovery.

Herlah B, Janežič M, Ogris I, Grdadolnik SG, Kološa K, Žabkar S, Žegura B, Perdih A. Herlah B, et al. Among authors: janezic m. Biomed Pharmacother. 2024 Jun;175:116676. doi: 10.1016/j.biopha.2024.116676. Epub 2024 May 20. Biomed Pharmacother. 2024. PMID: 38772152 Free article.

10

¹ H-¹⁵ N HMBC NMR as a tool for rapid identification of isomeric azaindoles: The case of 5F-MDMB-P7AICA.

Martek BA, Mihelač M, Gazvoda M, Virant M, Urankar D, Krivec M, Gostič T, Nemec B, Koštrun B, Janežič M, Klemenc S, Košmrlj J. Martek BA, et al. Among authors: janezic m. Drug Test Anal. 2019 Apr;11(4):617-625. doi: 10.1002/dta.2573. Epub 2019 Feb 26. Drug Test Anal. 2019. PMID: 30730110

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