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Wnt-β-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression.
Quandt J, Arnovitz S, Haghi L, Woehlk J, Mohsin A, Okoreeh M, Mathur PS, Emmanuel AO, Osman A, Krishnan M, Morin SB, Pearson AT, Sweis RF, Pekow J, Weber CR, Khazaie K, Gounari F. Quandt J, et al. Among authors: khazaie k. Nat Immunol. 2021 Apr;22(4):471-484. doi: 10.1038/s41590-021-00889-2. Epub 2021 Mar 4. Nat Immunol. 2021. PMID: 33664518 Free PMC article.
β-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells.
Keerthivasan S, Aghajani K, Dose M, Molinero L, Khan MW, Venkateswaran V, Weber C, Emmanuel AO, Sun T, Bentrem DJ, Mulcahy M, Keshavarzian A, Ramos EM, Blatner N, Khazaie K, Gounari F. Keerthivasan S, et al. Among authors: khazaie k. Sci Transl Med. 2014 Feb 26;6(225):225ra28. doi: 10.1126/scitranslmed.3007607. Sci Transl Med. 2014. PMID: 24574339 Free PMC article.
TCF-1: a maverick in T cell development and function.
Gounari F, Khazaie K. Gounari F, et al. Among authors: khazaie k. Nat Immunol. 2022 May;23(5):671-678. doi: 10.1038/s41590-022-01194-2. Epub 2022 Apr 29. Nat Immunol. 2022. PMID: 35487986 Free PMC article. Review.
Preferential expansion of pro-inflammatory Tregs in human non-small cell lung cancer.
Phillips JD, Knab LM, Blatner NR, Haghi L, DeCamp MM, Meyerson SL, Heiferman MJ, Heiferman JR, Gounari F, Bentrem DJ, Khazaie K. Phillips JD, et al. Among authors: khazaie k. Cancer Immunol Immunother. 2015 Sep;64(9):1185-91. doi: 10.1007/s00262-015-1725-1. Epub 2015 Jun 6. Cancer Immunol Immunother. 2015. PMID: 26047578 Free PMC article.
Cell Intrinsic Deregulated ß-Catenin Signaling Promotes Expansion of Bone Marrow Derived Connective Tissue Type Mast Cells, Systemic Inflammation, and Colon Cancer.
Saadalla A, Lima MM, Tsai F, Osman A, Singh MP, Linden DR, Dennis KL, Haeryfar SMM, Gurish MF, Gounari F, Khazaie K. Saadalla A, et al. Among authors: khazaie k. Front Immunol. 2019 Dec 3;10:2777. doi: 10.3389/fimmu.2019.02777. eCollection 2019. Front Immunol. 2019. PMID: 31849960 Free PMC article.
129 results