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Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound.
Cale EM, Bai H, Bose M, Messina MA, Colby DJ, Sanders-Buell E, Dearlove B, Li Y, Engeman E, Silas D, O'Sullivan AM, Mann B, Pinyakorn S, Intasan J, Benjapornpong K, Sacdalan C, Kroon E, Phanuphak N, Gramzinski R, Vasan S, Robb ML, Michael NL, Lynch RM, Bailer RT, Pagliuzza A, Chomont N, Pegu A, Doria-Rose NA, Trautmann L, Crowell TA, Mascola JR, Ananworanich J, Tovanabutra S, Rolland M; RV397 Study Group. Cale EM, et al. Among authors: engeman e. J Clin Invest. 2020 Jun 1;130(6):3299-3304. doi: 10.1172/JCI134395. J Clin Invest. 2020. PMID: 32182219 Free PMC article. Clinical Trial.