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Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins.
Chen F, Tzarum N, Lin X, Giang E, Velázquez-Moctezuma R, Augestad EH, Nagy K, He L, Hernandez M, Fouch ME, Grinyó A, Chavez D, Doranz BJ, Prentoe J, Stanfield RL, Lanford R, Bukh J, Wilson IA, Zhu J, Law M. Chen F, et al. Among authors: lin x. Immunity. 2021 Apr 13;54(4):781-796.e4. doi: 10.1016/j.immuni.2021.02.013. Epub 2021 Mar 5. Immunity. 2021. PMID: 33675683 Free PMC article.
HIV-1 vaccine design through minimizing envelope metastability.
He L, Kumar S, Allen JD, Huang D, Lin X, Mann CJ, Saye-Francisco KL, Copps J, Sarkar A, Blizard GS, Ozorowski G, Sok D, Crispin M, Ward AB, Nemazee D, Burton DR, Wilson IA, Zhu J. He L, et al. Among authors: lin x. Sci Adv. 2018 Nov 21;4(11):eaau6769. doi: 10.1126/sciadv.aau6769. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30474059 Free PMC article.
A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.
Kumar S, Ju B, Shapero B, Lin X, Ren L, Zhang L, Li D, Zhou Z, Feng Y, Sou C, Mann CJ, Hao Y, Sarkar A, Hou J, Nunnally C, Hong K, Wang S, Ge X, Su B, Landais E, Sok D, Zwick MB, He L, Zhu J, Wilson IA, Shao Y. Kumar S, et al. Among authors: lin x. Sci Adv. 2020 Sep 16;6(38):eabb1328. doi: 10.1126/sciadv.abb1328. Print 2020 Sep. Sci Adv. 2020. PMID: 32938661 Free PMC article.
Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates.
He L, Lin X, Wang Y, Abraham C, Sou C, Ngo T, Zhang Y, Wilson IA, Zhu J. He L, et al. Among authors: lin x. bioRxiv [Preprint]. 2021 Apr 5:2020.09.14.296715. doi: 10.1101/2020.09.14.296715. bioRxiv. 2021. Update in: Sci Adv. 2021 Mar 19;7(12):eabf1591. doi: 10.1126/sciadv.abf1591 PMID: 32995773 Free PMC article. Updated. Preprint.
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