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Evaluation of global conformational changes in peptides and proteins following purification by supercritical fluid chromatography.
Schiavone NM, Bennett R, Hicks MB, Pirrone GF, Regalado EL, Mangion I, Makarov AA. Schiavone NM, et al. Among authors: mangion i. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Mar 15;1110-1111:94-100. doi: 10.1016/j.jchromb.2019.02.012. Epub 2019 Feb 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 30785083
Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug substances.
Haidar Ahmad IA , Chen W , Halsey HM , Klapars A , Limanto J , Pirrone GF , Nowak T , Bennett R , Hartman R , Makarov AA , Mangion I , Regalado EL . Haidar Ahmad IA , et al. Among authors: mangion i. Analyst. 2019 Apr 23;144(9):2872-2880. doi: 10.1039/c8an02499e. Analyst. 2019. PMID: 30830135
Chaotropic Effects in Sub/Supercritical Fluid Chromatography via Ammonium Hydroxide in Water-Rich Modifiers: Enabling Separation of Peptides and Highly Polar Pharmaceuticals at the Preparative Scale.
Liu J, Makarov AA, Bennett R, Haidar Ahmad IA, DaSilva J, Reibarkh M, Mangion I, Mann BF, Regalado EL. Liu J, et al. Among authors: mangion i. Anal Chem. 2019 Nov 5;91(21):13907-13915. doi: 10.1021/acs.analchem.9b03408. Epub 2019 Oct 8. Anal Chem. 2019. PMID: 31549812
52 results