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Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies.
Jiang KL, Tong LX, Wang T, Wang HL, Hu XB, Xu GY, Jin TT, Kan WJ, Xu L, Li JN, Zhang KX, Song N, Liu JY, Zhang MM, Wu WB, Xiang YQ, Gao AH, Hu YZ, Zhou YB, Liu T, Yang JM, Li J. Jiang KL, et al. Among authors: li jn, li j. Acta Pharmacol Sin. 2022 Jan;43(1):220-228. doi: 10.1038/s41401-021-00652-1. Epub 2021 Mar 29. Acta Pharmacol Sin. 2022. PMID: 33782542 Free PMC article.
Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies.
Saidahmatov A, Li J, Xu S, Hu X, Gao X, Kan W, Gao L, Li C, Shi Y, Sheng L, Wang P, Zhou Y, Liang X, Li J, Liu H. Saidahmatov A, et al. J Med Chem. 2024 Sep 12;67(17):15220-15245. doi: 10.1021/acs.jmedchem.4c00837. Epub 2024 Aug 23. J Med Chem. 2024. PMID: 39178382
Integrative proteogenomic and pharmacological landscape of acute myeloid leukaemia.
Wang H, Xu JY, Wang T, Xu G, Luo G, Zhang M, Tang G, Wang C, Wang L, Fu W, Ni X, Zhai L, Xu R, Li J, Ye Y, Qiu X, Wu Z, Li J, Zhou Y, Yang J, Tan M, Li J. Wang H, et al. Sci Bull (Beijing). 2024 Nov 19:S2095-9273(24)00826-0. doi: 10.1016/j.scib.2024.11.020. Online ahead of print. Sci Bull (Beijing). 2024. PMID: 39609214 No abstract available.
540 results