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Page 1
Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors.
Ortiz DF, Lansing JC, Rutitzky L, Kurtagic E, Prod'homme T, Choudhury A, Washburn N, Bhatnagar N, Beneduce C, Holte K, Prenovitz R, Child M, Killough J, Tyler S, Brown J, Nguyen S, Schwab I, Hains M, Meccariello R, Markowitz L, Wang J, Zouaoui R, Simpson A, Schultes B, Capila I, Ling L, Nimmerjahn F, Manning AM, Bosques CJ. Ortiz DF, et al. Sci Transl Med. 2016 Nov 16;8(365):365ra158. doi: 10.1126/scitranslmed.aaf9418. Sci Transl Med. 2016. PMID: 27856797
Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity.
Washburn N, Schwab I, Ortiz D, Bhatnagar N, Lansing JC, Medeiros A, Tyler S, Mekala D, Cochran E, Sarvaiya H, Garofalo K, Meccariello R, Meador JW 3rd, Rutitzky L, Schultes BC, Ling L, Avery W, Nimmerjahn F, Manning AM, Kaundinya GV, Bosques CJ. Washburn N, et al. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1297-306. doi: 10.1073/pnas.1422481112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733881 Free PMC article.
Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice.
Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG. Stobdan T, et al. Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10425-30. doi: 10.1073/pnas.1507486112. Epub 2015 Aug 3. Proc Natl Acad Sci U S A. 2015. PMID: 26240367 Free PMC article.
Transport of nitric oxide by perfluorocarbon emulsion.
Ortiz D, Cabrales P, Briceño JC. Ortiz D, et al. Biotechnol Prog. 2013 Nov-Dec;29(6):1565-72. doi: 10.1002/btpr.1797. Epub 2013 Sep 10. Biotechnol Prog. 2013. PMID: 23966236 Free PMC article.
34 results