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Page 1
A Therapeutic Strategy for Preferential Targeting of TET2 Mutant and TET-dioxygenase Deficient Cells in Myeloid Neoplasms.
Guan Y, Tiwari AD, Phillips JG, Hasipek M, Grabowski DR, Pagliuca S, Gopal P, Kerr CM, Adema V, Radivoyevitch T, Parker Y, Lindner DJ, Meggendorfer M, Abazeed M, Sekeres MA, Mian OY, Haferlach T, Maciejewski JP, Jha BK. Guan Y, et al. Among authors: hasipek m. Blood Cancer Discov. 2021 Mar;2(2):146-161. doi: 10.1158/2643-3230.BCD-20-0173. Epub 2020 Dec 7. Blood Cancer Discov. 2021. PMID: 33681816 Free PMC article.
Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia.
Guan Y, Greenberg EF, Hasipek M, Chen S, Liu X, Kerr CM, Gackowski D, Zarakowska E, Radivoyevitch T, Gu X, Willard B, Visconte V, Makishima H, Nazha A, Mukherji M, Sekeres MA, Saunthararajah Y, Oliński R, Xu M, Maciejewski JP, Jha BK. Guan Y, et al. Among authors: hasipek m. Commun Biol. 2020 Sep 7;3(1):493. doi: 10.1038/s42003-020-01220-9. Commun Biol. 2020. PMID: 32895473 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34238758
Eltrombopag inhibits TET dioxygenase to contribute to hematopoietic stem cell expansion in aplastic anemia.
Guan Y, Hasipek M, Jiang D, Tiwari AD, Grabowski DR, Pagliuca S, Kongkiatkamon S, Patel B, Singh S, Parker Y, LaFramboise T, Lindner D, Sekeres MA, Mian OY, Saunthararajah Y, Maciejewski JP, Jha BK. Guan Y, et al. Among authors: hasipek m. J Clin Invest. 2022 Feb 15;132(4):e149856. doi: 10.1172/JCI149856. J Clin Invest. 2022. PMID: 35085104 Free PMC article.
Therapeutic Targeting of Protein Disulfide Isomerase PDIA1 in Multiple Myeloma.
Hasipek M, Grabowski D, Guan Y, Alugubelli RR, Tiwari AD, Gu X, DeAvila GA, Silva AS, Meads MB, Parker Y, Lindner DJ, Saunthararajah Y, Shain KH, Maciejewski JP, Reu FJ, Phillips JG, Jha BK. Hasipek M, et al. Cancers (Basel). 2021 May 28;13(11):2649. doi: 10.3390/cancers13112649. Cancers (Basel). 2021. PMID: 34071205 Free PMC article.
Rare germline alterations of myeloperoxidase predispose to myeloid neoplasms.
Kongkiatkamon S, Terkawi L, Guan Y, Adema V, Hasipek M, Dombrovski T, Co M, Walter W, Awada H, Parker Y, Hutter S, Pagliuca S, Gurnari C, Rogers HJ, Meggendorfer M, Lindner DJ, Haferlach T, Visconte V, LaFramboise T, Jha BK, Maciejewski JP. Kongkiatkamon S, et al. Among authors: hasipek m. Leukemia. 2022 Aug;36(8):2086-2096. doi: 10.1038/s41375-022-01630-0. Epub 2022 Jun 27. Leukemia. 2022. PMID: 35761024
Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates.
Gu X, Ebrahem Q, Mahfouz RZ, Hasipek M, Enane F, Radivoyevitch T, Rapin N, Przychodzen B, Hu Z, Balusu R, Cotta CV, Wald D, Argueta C, Landesman Y, Martelli MP, Falini B, Carraway H, Porse BT, Maciejewski J, Jha BK, Saunthararajah Y. Gu X, et al. Among authors: hasipek m. J Clin Invest. 2018 Oct 1;128(10):4260-4279. doi: 10.1172/JCI97117. Epub 2018 Jul 17. J Clin Invest. 2018. PMID: 30015632 Free PMC article.
Decitabine- and 5-azacytidine resistance emerges from adaptive responses of the pyrimidine metabolism network.
Gu X, Tohme R, Tomlinson B, Sakre N, Hasipek M, Durkin L, Schuerger C, Grabowski D, Zidan AM, Radivoyevitch T, Hong C, Carraway H, Hamilton B, Sobecks R, Patel B, Jha BK, Hsi ED, Maciejewski J, Saunthararajah Y. Gu X, et al. Among authors: hasipek m. Leukemia. 2021 Apr;35(4):1023-1036. doi: 10.1038/s41375-020-1003-x. Epub 2020 Aug 7. Leukemia. 2021. PMID: 32770088 Free PMC article.
Multiple Myeloma Therapy: Emerging Trends and Challenges.
Dima D, Jiang D, Singh DJ, Hasipek M, Shah HS, Ullah F, Khouri J, Maciejewski JP, Jha BK. Dima D, et al. Among authors: hasipek m. Cancers (Basel). 2022 Aug 23;14(17):4082. doi: 10.3390/cancers14174082. Cancers (Basel). 2022. PMID: 36077618 Free PMC article. Review.
17 results