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The emergence and ongoing convergent evolution of the N501Y lineages coincides with a major global shift in the SARS-CoV-2 selective landscape.
Martin DP, Weaver S, Tegally H, San EJ, Shank SD, Wilkinson E, Lucaci AG, Giandhari J, Naidoo S, Pillay Y, Singh L, Lessells RJ; NGS-SA; COVID-19 Genomics UK (COG-UK); Gupta RK, Wertheim JO, Nekturenko A, Murrell B, Harkins GW, Lemey P, MacLean OA, Robertson DL, de Oliveira T, Kosakovsky Pond SL. Martin DP, et al. Among authors: singh l. medRxiv [Preprint]. 2021 Jul 25:2021.02.23.21252268. doi: 10.1101/2021.02.23.21252268. medRxiv. 2021. Update in: Cell. 2021 Sep 30;184(20):5189-5200.e7. doi: 10.1016/j.cell.2021.09.003 PMID: 33688681 Free PMC article. Updated. Preprint.
Early transmission of SARS-CoV-2 in South Africa: An epidemiological and phylogenetic report.
Giandhari J, Pillay S, Wilkinson E, Tegally H, Sinayskiy I, Schuld M, Lourenco J, Chimukangara B, Lessells R, Moosa Y, Gazy I, Fish M, Singh L, Khanyile KS, Fonseca V, Giovanetti M, Alcantara LC, Petruccione F, de Oliveira T. Giandhari J, et al. Among authors: singh l. medRxiv [Preprint]. 2020 May 29:2020.05.29.20116376. doi: 10.1101/2020.05.29.20116376. medRxiv. 2020. Update in: Int J Infect Dis. 2021 Feb;103:234-241. doi: 10.1016/j.ijid.2020.11.128 PMID: 32511505 Free PMC article. Updated. Preprint.
Whole Genome Sequencing of SARS-CoV-2: Adapting Illumina Protocols for Quick and Accurate Outbreak Investigation during a Pandemic.
Pillay S, Giandhari J, Tegally H, Wilkinson E, Chimukangara B, Lessells R, Moosa Y, Mattison S, Gazy I, Fish M, Singh L, Khanyile KS, San JE, Fonseca V, Giovanetti M, Alcantara LC Jr, de Oliveira T. Pillay S, et al. Among authors: singh l. Genes (Basel). 2020 Aug 17;11(8):949. doi: 10.3390/genes11080949. Genes (Basel). 2020. PMID: 32824573 Free PMC article.
Early transmission of SARS-CoV-2 in South Africa: An epidemiological and phylogenetic report.
Giandhari J, Pillay S, Wilkinson E, Tegally H, Sinayskiy I, Schuld M, Lourenço J, Chimukangara B, Lessells R, Moosa Y, Gazy I, Fish M, Singh L, Sedwell Khanyile K, Fonseca V, Giovanetti M, Carlos Junior Alcantara L, Petruccione F, de Oliveira T. Giandhari J, et al. Among authors: singh l. Int J Infect Dis. 2021 Feb;103:234-241. doi: 10.1016/j.ijid.2020.11.128. Epub 2020 Nov 12. Int J Infect Dis. 2021. PMID: 33189939 Free PMC article.
High Resolution analysis of Transmission Dynamics of Sars-Cov-2 in Two Major Hospital Outbreaks in South Africa Leveraging Intrahost Diversity.
James SE, Ngcapu S, Kanzi AM, Tegally H, Fonseca V, Giandhari J, Wilkinson E, Chimukangara B, Pillay S, Singh L, Fish M, Gazy I, Khanyile K, Lessells R, de Oliveira T. James SE, et al. Among authors: singh l. medRxiv [Preprint]. 2020 Nov 16:2020.11.15.20231993. doi: 10.1101/2020.11.15.20231993. medRxiv. 2020. Update in: Virus Evol. 2021 Apr 21;7(1):veab041. doi: 10.1093/ve/veab041 PMID: 33236025 Free PMC article. Updated. Preprint.
PCR assay to enhance global surveillance for SARS-CoV-2 variants of concern.
Vogels CBF, Breban MI, Alpert T, Petrone ME, Watkins AE, Ott IM, de Jesus JG, Claro IM, Ferreira GM, Crispim MAE; Brazil-UK CADDE Genomic Network; Singh L, Tegally H, Anyaneji UJ; NGS-SA; Hodcroft EB, Mason CE, Khullar G, Metti J, Dudley JT, MacKay MJ, Nash M, Wang J, Liu C, Hui P, Murphy S, Neal C, Laszlo E, Landry ML, Muyombwe A, Downing R, Razeq J, de Oliveira T, Faria NR, Sabino EC, Neher RA, Fauver JR, Grubaugh ND. Vogels CBF, et al. Among authors: singh l. medRxiv [Preprint]. 2021 Mar 12:2021.01.28.21250486. doi: 10.1101/2021.01.28.21250486. medRxiv. 2021. Update in: PLoS Biol. 2021 May 7;19(5):e3001236. doi: 10.1371/journal.pbio.3001236 PMID: 33758901 Free PMC article. Updated. Preprint.
Transmission dynamics of SARS-CoV-2 within-host diversity in two major hospital outbreaks in South Africa.
San JE, Ngcapu S, Kanzi AM, Tegally H, Fonseca V, Giandhari J, Wilkinson E, Nelson CW, Smidt W, Kiran AM, Chimukangara B, Pillay S, Singh L, Fish M, Gazy I, Martin DP, Khanyile K, Lessells R, de Oliveira T. San JE, et al. Among authors: singh l. Virus Evol. 2021 Apr 21;7(1):veab041. doi: 10.1093/ve/veab041. eCollection 2021 Jan. Virus Evol. 2021. PMID: 34035952 Free PMC article.
The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages.
Martin DP, Weaver S, Tegally H, San JE, Shank SD, Wilkinson E, Lucaci AG, Giandhari J, Naidoo S, Pillay Y, Singh L, Lessells RJ; NGS-SA; COVID-19 Genomics UK (COG-UK); Gupta RK, Wertheim JO, Nekturenko A, Murrell B, Harkins GW, Lemey P, MacLean OA, Robertson DL, de Oliveira T, Kosakovsky Pond SL. Martin DP, et al. Among authors: singh l. Cell. 2021 Sep 30;184(20):5189-5200.e7. doi: 10.1016/j.cell.2021.09.003. Epub 2021 Sep 7. Cell. 2021. PMID: 34537136 Free PMC article.
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa.
Wilkinson E, Giovanetti M, Tegally H, San JE, Lessells R, Cuadros D, Martin DP, Rasmussen DA, Zekri AN, Sangare AK, Ouedraogo AS, Sesay AK, Priscilla A, Kemi AS, Olubusuyi AM, Oluwapelumi AOO, Hammami A, Amuri AA, Sayed A, Ouma AEO, Elargoubi A, Ajayi NA, Victoria AF, Kazeem A, George A, Trotter AJ, Yahaya AA, Keita AK, Diallo A, Kone A, Souissi A, Chtourou A, Gutierrez AV, Page AJ, Vinze A, Iranzadeh A, Lambisia A, Ismail A, Rosemary A, Sylverken A, Femi A, Ibrahimi A, Marycelin B, Oderinde BS, Bolajoko B, Dhaala B, Herring BL, Njanpop-Lafourcade BM, Kleinhans B, McInnis B, Tegomoh B, Brook C, Pratt CB, Scheepers C, Akoua-Koffi CG, Agoti CN, Peyrefitte C, Daubenberger C, Morang'a CM, Nokes DJ, Amoako DG, Bugembe DL, Park D, Baker D, Doolabh D, Ssemwanga D, Tshiabuila D, Bassirou D, Amuzu DSY, Goedhals D, Omuoyo DO, Maruapula D, Foster-Nyarko E, Lusamaki EK, Simulundu E, Ong'era EM, Ngabana EN, Shumba E, El Fahime E, Lokilo E, Mukantwari E, Philomena E, Belarbi E, Simon-Loriere E, Anoh EA, Leendertz F, Ajili F, Enoch FO, Wasfi F, Abdelmoula F, Mosha FS, Takawira FT, Derrar F, Bouzid F, Onikepe F, Adeola F, Muyembe FM, Tanser F, Dratibi FA, Mbunsu GK, Thilliez G, Kay GL, Githinji G… See abstract for full author list ➔ Wilkinson E, et al. Among authors: singh l. Science. 2021 Oct 22;374(6566):423-431. doi: 10.1126/science.abj4336. Epub 2021 Sep 9. Science. 2021. PMID: 34672751 Free PMC article.
2,039 results