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Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip® assay in TK6 cells.
Buick JK, Rowan-Carroll A, Gagné R, Williams A, Chen R, Li HH, Fornace AJ Jr, Chao C, Engelward BP, Frötschl R, Ellinger-Ziegelbauer H, Pettit SD, Aubrecht J, Yauk CL. Buick JK, et al. Front Toxicol. 2022 Sep 23;4:991590. doi: 10.3389/ftox.2022.991590. eCollection 2022. Front Toxicol. 2022. PMID: 36211197 Free PMC article.
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.
Corton JC, Mitchell CA, Auerbach S, Bushel P, Ellinger-Ziegelbauer H, Escobar PA, Froetschl R, Harrill AH, Johnson K, Klaunig JE, Pandiri AR, Podtelezhnikov AA, Rager JE, Tanis KQ, van der Laan JW, Vespa A, Yauk CL, Pettit SD, Sistare FD. Corton JC, et al. Among authors: pettit sd. Toxicol Sci. 2022 Jun 28;188(1):4-16. doi: 10.1093/toxsci/kfac041. Toxicol Sci. 2022. PMID: 35404422 Free PMC article.
A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.
Johnson KJ, Auerbach SS, Stevens T, Barton-Maclaren TS, Costa E, Currie RA, Dalmas Wilk D, Haq S, Rager JE, Reardon AJF, Wehmas L, Williams A, O'Brien J, Yauk C, LaRocca JL, Pettit S. Johnson KJ, et al. Among authors: pettit s. Toxicol Sci. 2022 Nov 23;190(2):127-132. doi: 10.1093/toxsci/kfac097. Toxicol Sci. 2022. PMID: 36165699 Free PMC article.
Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories.
Boedigheimer MJ, Wolfinger RD, Bass MB, Bushel PR, Chou JW, Cooper M, Corton JC, Fostel J, Hester S, Lee JS, Liu F, Liu J, Qian HR, Quackenbush J, Pettit S, Thompson KL. Boedigheimer MJ, et al. Among authors: pettit s. BMC Genomics. 2008 Jun 12;9:285. doi: 10.1186/1471-2164-9-285. BMC Genomics. 2008. PMID: 18549499 Free PMC article.
Database development in toxicogenomics: issues and efforts.
Mattes WB, Pettit SD, Sansone SA, Bushel PR, Waters MD. Mattes WB, et al. Environ Health Perspect. 2004 Mar;112(4):495-505. doi: 10.1289/ehp.6697. Environ Health Perspect. 2004. PMID: 15033600 Free PMC article. Review.
291 results