Hanson G - Search Results

1

A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome.

Erdos MR, Cabral WA, Tavarez UL, Cao K, Gvozdenovic-Jeremic J, Narisu N, Zerfas PM, Crumley S, Boku Y, Hanson G, Mourich DV, Kole R, Eckhaus MA, Gordon LB, Collins FS. Erdos MR, et al. Among authors: hanson g. Nat Med. 2021 Mar;27(3):536-545. doi: 10.1038/s41591-021-01274-0. Epub 2021 Mar 11. Nat Med. 2021. PMID: 33707773 Free PMC article.

2

Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers.

Li C, Callahan AJ, Simon MD, Totaro KA, Mijalis AJ, Phadke KS, Zhang G, Hartrampf N, Schissel CK, Zhou M, Zong H, Hanson GJ, Loas A, Pohl NLB, Verhoeven DE, Pentelute BL. Li C, et al. Among authors: hanson gj. Nat Commun. 2021 Jul 20;12(1):4396. doi: 10.1038/s41467-021-24598-4. Nat Commun. 2021. PMID: 34285203 Free PMC article.

3

Perfluoroaryl Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides.

Wolfe JM, Fadzen CM, Holden RL, Yao M, Hanson GJ, Pentelute BL. Wolfe JM, et al. Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4756-4759. doi: 10.1002/anie.201801167. Epub 2018 Mar 14. Angew Chem Int Ed Engl. 2018. PMID: 29479836 Free PMC article.

4

Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy.

Fadzen CM, Holden RL, Wolfe JM, Choo ZN, Schissel CK, Yao M, Hanson GJ, Pentelute BL. Fadzen CM, et al. Biochemistry. 2019 Sep 24;58(38):3980-3989. doi: 10.1021/acs.biochem.9b00413. Epub 2019 Sep 6. Biochemistry. 2019. PMID: 31450889

5

A cell-penetrating peptide enhances delivery and efficacy of phosphorodiamidate morpholino oligomers in mdx mice.

Gan L, Wu LCL, Wood JA, Yao M, Treleaven CM, Estrella NL, Wentworth BM, Hanson GJ, Passini MA. Gan L, et al. Mol Ther Nucleic Acids. 2022 Aug 17;30:17-27. doi: 10.1016/j.omtn.2022.08.019. eCollection 2022 Dec 13. Mol Ther Nucleic Acids. 2022. PMID: 36189424 Free PMC article.

6

Systemic PPMO-mediated dystrophin expression in the Dup2 mouse model of Duchenne muscular dystrophy.

Gushchina LV, Vetter TA, Frair EC, Bradley AJ, Grounds KM, Lay JW, Huang N, Suhaiba A, Schnell FJ, Hanson G, Simmons TR, Wein N, Flanigan KM. Gushchina LV, et al. Among authors: hanson g. Mol Ther Nucleic Acids. 2022 Nov 9;30:479-492. doi: 10.1016/j.omtn.2022.10.025. eCollection 2022 Dec 13. Mol Ther Nucleic Acids. 2022. PMID: 36420217 Free PMC article.

7

Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery.

Wolfe JM, Fadzen CM, Choo ZN, Holden RL, Yao M, Hanson GJ, Pentelute BL. Wolfe JM, et al. ACS Cent Sci. 2018 Apr 25;4(4):512-520. doi: 10.1021/acscentsci.8b00098. Epub 2018 Apr 5. ACS Cent Sci. 2018. PMID: 29721534 Free PMC article.

8

Systemic Antisense Therapeutics for Dystrophin and Myostatin Exon Splice Modulation Improve Muscle Pathology of Adult mdx Mice.

Lu-Nguyen N, Malerba A, Popplewell L, Schnell F, Hanson G, Dickson G. Lu-Nguyen N, et al. Among authors: hanson g. Mol Ther Nucleic Acids. 2017 Mar 17;6:15-28. doi: 10.1016/j.omtn.2016.11.009. Epub 2016 Dec 10. Mol Ther Nucleic Acids. 2017. PMID: 28325281 Free PMC article.

9

Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice.

Lu-Nguyen N, Ferry A, Schnell FJ, Hanson GJ, Popplewell L, Dickson G, Malerba A. Lu-Nguyen N, et al. Among authors: hanson gj. Hum Mol Genet. 2019 Sep 15;28(18):3091-3100. doi: 10.1093/hmg/ddz125. Hum Mol Genet. 2019. PMID: 31179493

10

Host-microbiome determinants of ready-to-use supplemental food efficacy in acute childhood malnutrition.

Jamil Z, Hanson GF, Iqbal J, Moreau GB, Iqbal NT, Ahmed S, Hotwani A, Kabir F, Umrani F, Sadiq K, Ahmed K, Mallawaarachchi I, Ma JZ, Aziz F, Ali SA, Moore S. Jamil Z, et al. Among authors: hanson gf. medRxiv [Preprint]. 2024 Dec 13:2024.12.12.24318367. doi: 10.1101/2024.12.12.24318367. medRxiv. 2024. PMID: 39711734 Free PMC article. Preprint.

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